Why a mother's love really is priceless: It prevents illness even into middle age(?)
This is the old "correlation is causation" fallacy yet again. IQ was apparently not controlled for but there are pockets of high IQ among poor families and high IQ parents probably treat their children better on the whole and high IQ people have better health anyhow and would transmit that to their children genetically
You comfort them over a skinned knee in the playground, and coax them to sleep with a soothing lullaby. And being a nurturing mother could well pay dividends in later life by protecting your child from serious illnesses, scientists say.
Tender loving care in childhood was found to reduce a person’s risk of conditions including diabetes and heart disease in adulthood, according to researchers at Brandeis University in Boston.
They examined 1,000 people from low-income backgrounds, which has been shown by a wealth of previous research to be related to poorer health in later life and lower life expectancy. However, they found some people from disadvantaged families managed to buck this trend – and they tended to have had a loving mother.
Participants were recruited at an average age of 46 and had a full health check in hospital. They were asked about their mothers with questions such as ‘how much did she understand your problems and worries?’ and ‘How much time and attention did she give you when you needed it?
A decade later half of the people had metabolic syndrome – a major risk factors for heart disease, strokes and diabetes. It is a combination of symptoms including excess fat around the waist, high blood pressure, high cholesterol and insulin resistance, which affects around one in four people in the UK.
They found people in the lowest socio-economic category, with neither parent having finished school, had the highest rate of this condition – half of them were affected and regardless of their social mobility in later life.
‘The stresses of childhood can leave a biological residue that shows up in midlife. Yet, among those at risk for poor health, adults who had nurturing mothers in childhood fared better in physical health’
But although this high risk seemed to be ‘embedded’ from childhood, the researchers said, those who said their mothers were very nurturing were far less likely to have it.
Psychology professor Margie Lachman said events in childhood seem to leave a ‘biological residue’ on health during adult life. She said: ‘The fact that we can see these long-term effects from childhood into midlife is pretty dramatic.
‘We want to understand what it is about having a nurturing mother that allows you to escape the vulnerabilities of being in a low socioeconomic status background and wind up healthier than your counterparts.’
The authors suggest it could be a combination of empathy, teaching children ‘coping strategies’ to deal with stress so it does not affect their health and encouraging them to eat well and live a healthy lifestyle.
They did not look at how nurturing their fathers were but the authors believe they probably have a big influence too particularly for the next generation as parental roles are less rigid than they were when the people they studied were young.
Prof Lachman said the information could help devise training for parents about coping with their child’s stress, living a healthy lifestyle and having ‘control over their destiny’.
The study was published in the journal Psychological Science.
SOURCE
Scientists urge universities to axe alternative medicine courses
MORE than 400 doctors, medical researchers and scientists have formed a powerful lobby group to pressure universities to close down alternative medicine degrees.
Almost one in three Australian universities now offer courses in some form of alternative therapy or complementary medicine, including traditional Chinese herbal medicine, chiropractics, homeopathy, naturopathy, reflexology and aromatherapy.
But the new group, Friends of Science in Medicine, wrote to vice-chancellors this week, warning that by giving "undeserved credibility to what in many cases would be better described as quackery" and by "failing to champion evidence-based science and medicine", the universities are trashing their reputation as bastions of scientific rigour.
The group, which names world-renowned biologist Sir Gustav Nossal and the creator of the cervical cancer vaccine Professor Ian Frazer among its members, is also campaigning for private health insurance providers to stop providing rebates for alternative medical treatments.
A co-founder of the group, Emeritus Professor John Dwyer, of the University of NSW, who is also a government adviser on consumer health fraud, said it was distressing that 19 universities were now offering "degrees in pseudo science".
"It's deplorable, but we didn't realise how much concern there was out there for universities' reputations until we tapped into it," Professor Dwyer said. "We're saying enough is enough. Taxpayers' money should not be wasted on funding [these courses] … nor should government health insurance rebates be wasted on this nonsense."
Professor Dwyer said it was particularly galling that such courses were growing in popularity while, at the same time, the federal government was looking at ways to get the Therapeutic Goods Administration to enforce tougher proof-of-efficacy criteria for complementary medicines, following the release of a highly critical review by the Australian National Audit Office last September.
Of particular concern to the group is the increase in chiropractic courses, following the recent announcement of a new chiropractic science degree by Central Queensland University. More than 30 scientists, doctors and community advocates wrote to the vice-chancellor and health science deans at the university voicing their concern, which laid the foundations for Friends of Science in Medicine.
The groundswell of protest from medical professionals comes after a decision in Britain that means from this year it will no longer be possible to receive a degree from a publicly-funded university in areas of alternative medicine, including homeopathy and naturopathy.
German and British medical insurance providers are also in the process of removing alternative therapies from the list of treatments they will cover.
Australia's vice-chancellors will meet in March and Professor Dwyer said his group was aiming to get a commitment from them to endorse health courses only with evidence-based science.
The spokesman for Universities Australia said tertiary institutions were self-accrediting. "[They have] the autonomy … to ensure the quality and relevance of the courses they offer," he said.
The Tertiary Education Quality and Standards Agency, a government body set up to regulate higher education, refused to comment.
Most health funds pay rebates for alternative therapies under top cover polices. Private Healthcare Australia did not return the Herald's calls.
SOURCE
Saturday, January 28, 2012
Friday, January 27, 2012
Here we go again
Eating chocolate could stave off bowel cancer, say scientists. There are some sharp skeptical comments towards the end of the article
A study found having daily doses of cocoa reduced the risk of developing the disease. It is the latest piece of research to highlight the health benefits of the cocoa bean, most of which is harvested in West Africa.
Previous studies have found the seed is rich in particularly powerful natural antioxidants that destroy harmful molecules known as free radicals. And it has been suggested that eating chocolate with a high cocoa content could help to control diabetes, blood pressure and heart disease.
Dr Maria Arribas, of the Science and Technology Institute of Food and Nutrition in Spain, who led the latest study, said: 'Foods like cocoa, which is rich in polyphenols, seems to play an important role in protecting against disease.'
Dr Arribas and her team investigated if the food could stop rats from developing bowel cancer when exposed to tumour-causing chemicals.
Bowel cancer is a general term for cancer that begins in the large bowel and depending on where the cancer starts, it can sometimes be referred to as colon or rectal cancer.
One group of rats were fed a daily diet consisting of 12 per cent of cocoa for eight weeks, while another group were given a diet containing no cocoa.
After a period of time, both groups were exposed to a carcinogen called azoxymethane, which is used to induce colon cancer. Within four weeks of the toxin exposure rats began to develop intestinal cancers.
However, the researchers discovered the rats on the cocoa diets had a reduced number of pre-cancerous lesions compared to the control group. It is believed that the study, published in Molecular Nutrition and Food Research, is the first to suggest that cocoa could help prevent bowel cancer. Further research is now needed to explore how the raw material could benefit humans.
However Sarah Williams, a spokesperson from Cancer Research UK warned that too much chocolate can also have a negative impact.
Commenting on the study she said: 'This study involved rats in the lab who were fed very large quantities of cocoa over a number of weeks, so it’s impossible to conclude that that eating chocolate or drinking cocoa protects people against bowel cancer.
'But we do know that chocolate is high in fat and calories, so eating too much of it could lead you to put on weight. 'And being obese has been shown to increase the risk of bowel cancer, so eating lots of chocolate is unlikely to be a good way to cut the risk.'
She highlighted that eating a healthy diet with 'lots of fruit, veg and fibre and limiting red and processed meat, cutting down on alcohol, staying physically active and not smoking' are other ways to reduce the risk of cancer.
In England, bowel cancer is the third most common type of cancer and it is estimated that 16,000 people die from the disease each year.
SOURCE
McFlurry of trade brings record year
A nasty one for the food Fascists
WE DON'T know how many burgers they made, but the other numbers are big enough. McDonald's rang up record sales of $US27 billion ($25.6 billion) in 33,510 restaurants worldwide last year, an increase of 12 per cent, turning a profit of $US5.5 billion from the 68 million customers it serves each day.
Although there is no country breakdown, it seems Australia was a weak contributor, with our stronger dollar biting into earnings and its chief executive, Jim Skinner, noting "lagging consumer confidence as a result of the economic slowdown".
Just 34 new stores opened in Australia last year, McDonald's US filings reveal, lifting this country's total to 865. That compared with 177 new stores opened in China.
But Australia again lived up to its track record as a hotbed of new ideas for the fast food giant. Chicken McBites have just been launched in the US after being invented here and launched in 2010. The recent launch here of smoothies and frappes have resulted in good sales volumes.
"That's something we're really proud of," said a spokeswoman. "Lots of innovation in McDonald's starts in Australia, like McCafes."
In what feel like hard economic times, McDonald's is trying to focus on value. "The McValue lunch has been very popular," the spokeswoman said.
Worldwide, said the chief operating officer, Donald Thompson, breakfast at McDonald's is booming, driven partly by local offerings such as McMuffins.
"Probably the biggest of all of the menu pieces I would say is breakfast. Breakfast is beginning to circulate around the rest of the world . .. there's some tremendous opportunity there. So we've got a lot of room still in breakfast products, the premium sandwiches. Wraps are travelling. McBites are in the US from Australia and smoothies and beverages are travelling around the world. So those things are going to continue."
In the December quarter, McDonald's reported sales of $US6.8 billion, up 10 per cent on the previous year, and net income of $US1.4 billion, up 11 per cent.
McDonald's does not give a country-by-country breakdown but the Asia-Pacific, Middle East and Africa were the strongest of its geographic regions, with sales up by 11 per cent both for the quarter, after stripping out currency impacts, compared with a year earlier, and for the 2011 full year.
SOURCE
Eating chocolate could stave off bowel cancer, say scientists. There are some sharp skeptical comments towards the end of the article
A study found having daily doses of cocoa reduced the risk of developing the disease. It is the latest piece of research to highlight the health benefits of the cocoa bean, most of which is harvested in West Africa.
Previous studies have found the seed is rich in particularly powerful natural antioxidants that destroy harmful molecules known as free radicals. And it has been suggested that eating chocolate with a high cocoa content could help to control diabetes, blood pressure and heart disease.
Dr Maria Arribas, of the Science and Technology Institute of Food and Nutrition in Spain, who led the latest study, said: 'Foods like cocoa, which is rich in polyphenols, seems to play an important role in protecting against disease.'
Dr Arribas and her team investigated if the food could stop rats from developing bowel cancer when exposed to tumour-causing chemicals.
Bowel cancer is a general term for cancer that begins in the large bowel and depending on where the cancer starts, it can sometimes be referred to as colon or rectal cancer.
One group of rats were fed a daily diet consisting of 12 per cent of cocoa for eight weeks, while another group were given a diet containing no cocoa.
After a period of time, both groups were exposed to a carcinogen called azoxymethane, which is used to induce colon cancer. Within four weeks of the toxin exposure rats began to develop intestinal cancers.
However, the researchers discovered the rats on the cocoa diets had a reduced number of pre-cancerous lesions compared to the control group. It is believed that the study, published in Molecular Nutrition and Food Research, is the first to suggest that cocoa could help prevent bowel cancer. Further research is now needed to explore how the raw material could benefit humans.
However Sarah Williams, a spokesperson from Cancer Research UK warned that too much chocolate can also have a negative impact.
Commenting on the study she said: 'This study involved rats in the lab who were fed very large quantities of cocoa over a number of weeks, so it’s impossible to conclude that that eating chocolate or drinking cocoa protects people against bowel cancer.
'But we do know that chocolate is high in fat and calories, so eating too much of it could lead you to put on weight. 'And being obese has been shown to increase the risk of bowel cancer, so eating lots of chocolate is unlikely to be a good way to cut the risk.'
She highlighted that eating a healthy diet with 'lots of fruit, veg and fibre and limiting red and processed meat, cutting down on alcohol, staying physically active and not smoking' are other ways to reduce the risk of cancer.
In England, bowel cancer is the third most common type of cancer and it is estimated that 16,000 people die from the disease each year.
SOURCE
McFlurry of trade brings record year
A nasty one for the food Fascists
WE DON'T know how many burgers they made, but the other numbers are big enough. McDonald's rang up record sales of $US27 billion ($25.6 billion) in 33,510 restaurants worldwide last year, an increase of 12 per cent, turning a profit of $US5.5 billion from the 68 million customers it serves each day.
Although there is no country breakdown, it seems Australia was a weak contributor, with our stronger dollar biting into earnings and its chief executive, Jim Skinner, noting "lagging consumer confidence as a result of the economic slowdown".
Just 34 new stores opened in Australia last year, McDonald's US filings reveal, lifting this country's total to 865. That compared with 177 new stores opened in China.
But Australia again lived up to its track record as a hotbed of new ideas for the fast food giant. Chicken McBites have just been launched in the US after being invented here and launched in 2010. The recent launch here of smoothies and frappes have resulted in good sales volumes.
"That's something we're really proud of," said a spokeswoman. "Lots of innovation in McDonald's starts in Australia, like McCafes."
In what feel like hard economic times, McDonald's is trying to focus on value. "The McValue lunch has been very popular," the spokeswoman said.
Worldwide, said the chief operating officer, Donald Thompson, breakfast at McDonald's is booming, driven partly by local offerings such as McMuffins.
"Probably the biggest of all of the menu pieces I would say is breakfast. Breakfast is beginning to circulate around the rest of the world . .. there's some tremendous opportunity there. So we've got a lot of room still in breakfast products, the premium sandwiches. Wraps are travelling. McBites are in the US from Australia and smoothies and beverages are travelling around the world. So those things are going to continue."
In the December quarter, McDonald's reported sales of $US6.8 billion, up 10 per cent on the previous year, and net income of $US1.4 billion, up 11 per cent.
McDonald's does not give a country-by-country breakdown but the Asia-Pacific, Middle East and Africa were the strongest of its geographic regions, with sales up by 11 per cent both for the quarter, after stripping out currency impacts, compared with a year earlier, and for the 2011 full year.
SOURCE
Thursday, January 26, 2012
Vitamin D deficiency in UK a 'major problem'
This is a disgrace. Official scares about avoiding skin cancer by staying out of the sun would have to be a major factor in this. Sun-loving Australians must get 1,000 times more sun exposure than Brits but skin cancer is only a minor problem among them, not even requiring surgery, usually. A quick spray with liquid nitrogen and that is the end of it usually
A quarter of all toddlers in the UK are lacking Vitamin D, according to research.
Vitamin D supplements are recommended for those people at risk of deficiency, including all pregnant and breastfeeding women, children under five, and the elderly, but 74 per cent of parents know nothing about them and more than half of healthcare professionals are also unaware, the BBC said.
Dr Benjamin Jacobs, consultant paediatrician at the Royal National Orthopaedic Hospital, described the issue as a "major problem". He told BBC Breakfast: "We see about one case of rickets a month in our hospital, but that's the very severe end of the disease. "There are many other children who have less severe problems - muscle weakness, delay in walking, bone pains - and research indicates that in many parts of the country the majority of children have a low level of Vitamin D."
He explained that it was discovered that Vitamin D prevents rickets about 100 years ago when most children in London suffered from the disease, and it was later eradicated.
But then, in the 1950s, there was concern that children were getting too much Vitamin D in food supplements and cod liver oil and supplements were stopped. This was unlike in other Western countries where they continued, he said. Dr Jacobs said: "We thought they were unnecessary, possibly harmful, and that was a major mistake."
He said parents are largely unaware of the risk of the condition, while health professionals are often taught that rickets is a disease of the past.
"It's really only over the past 10 years or so that I've noticed children with Vitamin D deficiency. and still I would say today, the majority of doctors, health visitors, midwives, nurses, are not aware enough of the problem," he said.
Asked about how vulnerable people can be given more Vitamin D, Dr Jacobs said current guidelines suggest taking drops or tablets, but experts are also looking into food supplementation.
He said it would not be harmful if people ended up with too much Vitamin D in their diet.
Current guidelines suggest that children and pregnant women should have 400 units a day, but he described this as a "conservative" level compared to the US, where he said a study suggested pregnant women should have 4,000 units. "In my view, it is extremely safe," he added.
Chief medical officer Professor Dame Sally Davies said the Government would be reviewing the issue. She said: "We know a significant proportion of people in the UK probably have inadequate levels of Vitamin D in their blood.
"People at risk of Vitamin D deficiency, including pregnant women and children under five, are already advised to take daily supplements. "Our experts are clear - low levels of Vitamin D can increase the risk of poor bone health, including rickets in young children.
"Many health professionals such as midwives, GPs and nurses give advice on supplements, and it is crucial they continue to offer this advice as part of routine consultations and ensure disadvantaged families have access to free Vitamin supplements through our Healthy Start scheme.
"It is important to raise awareness of this issue, and I will be contacting health professionals on the need to prescribe and recommend Vitamin D supplements to at-risk groups.
"The Department of Health has also asked the Scientific Advisory Committee on Nutrition to review the important issue of current dietary recommendations on Vitamin D."
SOURCE
Brain scans could diagnose dyslexic children before they even learn to read and head off difficulties at school
Some children with dyslexia go undiagnosed for years, leading to prolonged learning difficulties and children who are angry and frustrated at school. But all that could be a thing of the past.
Scientists now say they can identify the reading problem before children even start school, and long before they become labeled as poor students and begin to lose confidence in themselves.
Dyslexia typically is not identified until children are seven or eight and demonstrate real problems with their reading
Dyslexia typically is not identified until children are seven or eight and demonstrate real problems with their reading
Although children are not typically diagnosed with dyslexia until they are around 7 or 8 years old - a team from Children's Hospital Boston said they could see signs of the disease on brain scans in children as young as 4 or 5 years old.
This age is also when studies show children are most able to respond to interventions. 'We call it the dyslexia paradox,' said Nadine Gaab of the Laboratories of Cognitive Neuroscience at the hospital, whose study was published in Proceedings of the National Academy of Sciences.
Gaab said most children are not diagnosed until they demonstrate problems reading, but helping children with dyslexia works best if you start before they even begin to learn to read.
'Often, by the time they get a diagnosis, they usually have experienced three years of peers telling them they are stupid, parents telling them they are lazy. We know they have reduced self esteem. They are really struggling,' Gaab said.
Her study builds on an emerging understanding of dyslexia as a problem with recognizing and manipulating the individual sounds that form language - which is known as phonological processing.
In order to read, children must map the sounds of spoken language onto specific letters that make up words. Children with dyslexia struggle with this mapping process.
'The beauty is spoken language can present before written language so people can look for symptoms,' said Dr. Sally Shaywitz, a director of the Center for Dyslexia and Creativity at Yale University.
Signs of early dyslexia might include difficulty with rhyming, mispronouncing words or confusing similar-sounding words. 'Those are all very early symptoms,' Shaywitz said.
Dyslexia affects roughly 5 per cent to 17 per cent of all children. And up to 50 per cent of children with a family history of the disorder will struggle with reading, have poor spelling and experience difficulty decoding words.
In her study, Gaab and colleagues scanned the brains of 36 pre-school children while they did a number of tasks, such as trying to decide if two words start with the same sound.
They found that during these tasks, children who had a family history of dyslexia had less brain activity in certain regions of the brain than did children of similar ages, intelligence and socioeconomic status.
Older children and adults with dyslexia have dysfunction in these same areas of the brain, which include the junctions between the occipital and temporal lobes and the temporal and parietal lobes in the back of the brain. 'Often, by the time [children with dyslexia] get a diagnosis, they usually have experienced three years of peers telling them they are stupid'
Gaab said the study shows that when children predisposed to dyslexia did these tasks, their brains did not use the area typically used for processing this information. This problem occurred even before the children started learning to read.
'The important point of this paper is it shows the need to look for signs of dyslexia earlier,' said April Benasich, director of the Carter Center for Neurocognitive Research at Rutgers, the State University of New Jersey, who was not part of the study.
Benasich studies language processing in even younger children - babies who have a family history of learning disorders. 'There is evidence to suggest that what is thought to be reading failure is there before the kids fail,' she said.
Gaab said her study is too small to form the basis of any test for dyslexia but her team has just won a grant from the National Institutes of Health to do a larger study. Ultimately, she hopes parents will be able to go to their doctor and ask for their child to be assessed.
'Families often know that their child has dyslexia as early as kindergarten, but they can't get interventions at their schools,' she said in a statement. 'If we can show that we can identify these kids early, schools may be encouraged to develop programs.'
SOURCE
This is a disgrace. Official scares about avoiding skin cancer by staying out of the sun would have to be a major factor in this. Sun-loving Australians must get 1,000 times more sun exposure than Brits but skin cancer is only a minor problem among them, not even requiring surgery, usually. A quick spray with liquid nitrogen and that is the end of it usually
A quarter of all toddlers in the UK are lacking Vitamin D, according to research.
Vitamin D supplements are recommended for those people at risk of deficiency, including all pregnant and breastfeeding women, children under five, and the elderly, but 74 per cent of parents know nothing about them and more than half of healthcare professionals are also unaware, the BBC said.
Dr Benjamin Jacobs, consultant paediatrician at the Royal National Orthopaedic Hospital, described the issue as a "major problem". He told BBC Breakfast: "We see about one case of rickets a month in our hospital, but that's the very severe end of the disease. "There are many other children who have less severe problems - muscle weakness, delay in walking, bone pains - and research indicates that in many parts of the country the majority of children have a low level of Vitamin D."
He explained that it was discovered that Vitamin D prevents rickets about 100 years ago when most children in London suffered from the disease, and it was later eradicated.
But then, in the 1950s, there was concern that children were getting too much Vitamin D in food supplements and cod liver oil and supplements were stopped. This was unlike in other Western countries where they continued, he said. Dr Jacobs said: "We thought they were unnecessary, possibly harmful, and that was a major mistake."
He said parents are largely unaware of the risk of the condition, while health professionals are often taught that rickets is a disease of the past.
"It's really only over the past 10 years or so that I've noticed children with Vitamin D deficiency. and still I would say today, the majority of doctors, health visitors, midwives, nurses, are not aware enough of the problem," he said.
Asked about how vulnerable people can be given more Vitamin D, Dr Jacobs said current guidelines suggest taking drops or tablets, but experts are also looking into food supplementation.
He said it would not be harmful if people ended up with too much Vitamin D in their diet.
Current guidelines suggest that children and pregnant women should have 400 units a day, but he described this as a "conservative" level compared to the US, where he said a study suggested pregnant women should have 4,000 units. "In my view, it is extremely safe," he added.
Chief medical officer Professor Dame Sally Davies said the Government would be reviewing the issue. She said: "We know a significant proportion of people in the UK probably have inadequate levels of Vitamin D in their blood.
"People at risk of Vitamin D deficiency, including pregnant women and children under five, are already advised to take daily supplements. "Our experts are clear - low levels of Vitamin D can increase the risk of poor bone health, including rickets in young children.
"Many health professionals such as midwives, GPs and nurses give advice on supplements, and it is crucial they continue to offer this advice as part of routine consultations and ensure disadvantaged families have access to free Vitamin supplements through our Healthy Start scheme.
"It is important to raise awareness of this issue, and I will be contacting health professionals on the need to prescribe and recommend Vitamin D supplements to at-risk groups.
"The Department of Health has also asked the Scientific Advisory Committee on Nutrition to review the important issue of current dietary recommendations on Vitamin D."
SOURCE
Brain scans could diagnose dyslexic children before they even learn to read and head off difficulties at school
Some children with dyslexia go undiagnosed for years, leading to prolonged learning difficulties and children who are angry and frustrated at school. But all that could be a thing of the past.
Scientists now say they can identify the reading problem before children even start school, and long before they become labeled as poor students and begin to lose confidence in themselves.
Dyslexia typically is not identified until children are seven or eight and demonstrate real problems with their reading
Dyslexia typically is not identified until children are seven or eight and demonstrate real problems with their reading
Although children are not typically diagnosed with dyslexia until they are around 7 or 8 years old - a team from Children's Hospital Boston said they could see signs of the disease on brain scans in children as young as 4 or 5 years old.
This age is also when studies show children are most able to respond to interventions. 'We call it the dyslexia paradox,' said Nadine Gaab of the Laboratories of Cognitive Neuroscience at the hospital, whose study was published in Proceedings of the National Academy of Sciences.
Gaab said most children are not diagnosed until they demonstrate problems reading, but helping children with dyslexia works best if you start before they even begin to learn to read.
'Often, by the time they get a diagnosis, they usually have experienced three years of peers telling them they are stupid, parents telling them they are lazy. We know they have reduced self esteem. They are really struggling,' Gaab said.
Her study builds on an emerging understanding of dyslexia as a problem with recognizing and manipulating the individual sounds that form language - which is known as phonological processing.
In order to read, children must map the sounds of spoken language onto specific letters that make up words. Children with dyslexia struggle with this mapping process.
'The beauty is spoken language can present before written language so people can look for symptoms,' said Dr. Sally Shaywitz, a director of the Center for Dyslexia and Creativity at Yale University.
Signs of early dyslexia might include difficulty with rhyming, mispronouncing words or confusing similar-sounding words. 'Those are all very early symptoms,' Shaywitz said.
Dyslexia affects roughly 5 per cent to 17 per cent of all children. And up to 50 per cent of children with a family history of the disorder will struggle with reading, have poor spelling and experience difficulty decoding words.
In her study, Gaab and colleagues scanned the brains of 36 pre-school children while they did a number of tasks, such as trying to decide if two words start with the same sound.
They found that during these tasks, children who had a family history of dyslexia had less brain activity in certain regions of the brain than did children of similar ages, intelligence and socioeconomic status.
Older children and adults with dyslexia have dysfunction in these same areas of the brain, which include the junctions between the occipital and temporal lobes and the temporal and parietal lobes in the back of the brain. 'Often, by the time [children with dyslexia] get a diagnosis, they usually have experienced three years of peers telling them they are stupid'
Gaab said the study shows that when children predisposed to dyslexia did these tasks, their brains did not use the area typically used for processing this information. This problem occurred even before the children started learning to read.
'The important point of this paper is it shows the need to look for signs of dyslexia earlier,' said April Benasich, director of the Carter Center for Neurocognitive Research at Rutgers, the State University of New Jersey, who was not part of the study.
Benasich studies language processing in even younger children - babies who have a family history of learning disorders. 'There is evidence to suggest that what is thought to be reading failure is there before the kids fail,' she said.
Gaab said her study is too small to form the basis of any test for dyslexia but her team has just won a grant from the National Institutes of Health to do a larger study. Ultimately, she hopes parents will be able to go to their doctor and ask for their child to be assessed.
'Families often know that their child has dyslexia as early as kindergarten, but they can't get interventions at their schools,' she said in a statement. 'If we can show that we can identify these kids early, schools may be encouraged to develop programs.'
SOURCE
Wednesday, January 25, 2012
'Silent Thalidomide': Thousands of mothers and their daughters at risk of cancer from anti-miscarriage drugs they took decades ago
Tens of thousands of woman could suffer a rare cancer caused by a banned drug taken by their mothers or even grandmothers. The drug, Diethylstilboestrol (DES), was freely prescribed to pregnant women in Britain for three decades up to 1973, and was supposed to prevent miscarriages.
But it was belatedly banned in Britain after it was found to increase the risk of miscarriage – and it is now feared that it can lead to a deadly cancer to a second and even third generation.
Some 2,000 women have already sought compensation in America, with payouts totalling up to £1bn from the numerous drug companies that sold DES, while scores more are launching more legal action.
Now fresh compensation cases are set to begin here, with tens of thousands of British women to be asked if they could be potential victims of the drug nicknamed ‘the silent Thalidomide’.
As well as causing a rare cervical and vaginal cancer, and possibly breast cancer, in the daughters, and potentially grandchildren, of the women who took it long ago, DES is also being blamed for causing fertility problems.
The drug, a synthetic copy of the female hormone oestrogen, was created in Britain in 1938, and was soon being prescribed to millions of women around the world.
Doubts about the wisdom of using it surfaced in 1953, when an American study showed it caused more, rather than fewer miscarriages.
But it was not until 1971 that US authorities told doctors to stop prescribing it - after it was found that one in a thousand of the daughters of women prescribed DES had developed the cervical and vaginal cancer ‘clear cell adenocarcinoma’ (CCAC). And it was only in 1973 that British doctors were advised to stop prescribing the drug.
The Royal College of Obstetrics and Gynaecology has suggested 7,500 British women took DES, but there are other claims that up to 300,000 could be at risk.
Figures suggest that daughters of women who took the drug are made 40 times more likely to develop the cancer CCAC, often when young adults. The cancer is fatal in more than a quarter of cases. One study suggested that breast cancer risk is also doubled.
It will be impossible for many possible victims to find out, of course, whether their mothers or grandmothers used the drug.
Research on rodents has lent weight to the fear that DES dangerously alters DNA not only in the individual taking the drug, but also that those changes are passed on at least two generations.
Washington DC lawyer Aaron Devine, who is representing the 80 American women currently seeking compensation, is due in Britain in a fortnight to arrange a search for potential victims here.
The first woman in Britain found to have suffered as a result of DES taken by her mother is Heather Justice, 59, of Jarrow in Tyne and Wear. She was diagnosed with vaginal cancer aged 25, then went through a hysterectomy and other surgery. Records showed her mother had taken DES in the 1950s, but because she did not know which company produced it, has been unable to bring legal action.
Mrs Justice said: ‘One of the problems is that unlike Thalidomide, where you see the problem the minute the baby was born, women who took DES had healthy babies. ‘Problems were hidden until the teens and twenties, by which point we were forgotten about. When I asked my mum what she had taken, she didn’t even remember the name of the stuff. It is a complete and utter minefield.’
Among others who believe they have been afflicted in Britain are Janet Hall, 61, of Bournemouth - whose mother died from lung cancer aged 32 – who had to have much of her cervix removed when she was 20. She suffered a miscarriage, then had two daughters. One, Hannah, 26, has had pre-cancerous cells found in her cervix, she said. Mrs Hall said: ‘I feel guilty for my girls. It messes with your mind; it makes you ask why you had to have children.’
A spokesman for the Department of Health spoke of having ‘every sympathy’ for self-proclaimed victims, but said: ‘With regard to compensation for people who believe they have been adversely affected by this drug, this is a matter for the manufacturer(s) and/or the UK licensees of the drug.’
SOURCE
Packed lunches now "incorrect"
I took a packed lunch to school every day as a kid living in the tropics and came to no harm, nor did any other kid that I knew of.
SCHOOL children and workers who leave home with a packed lunch are at risk of food poisoning in warm weather, health experts say.
Four in five Australian workers take packed lunches, of which only half are kept cool, a Newspoll survey has found.
With bacteria growing quickly in warm weather, the likelihood of food poisoning is high, especially when cold meat, soft cheeses, pates and raw-egg mayonnaise are on the menu, the Food Safety Information Council says.
The risk is reduced by packing a frozen juice box, water bottle or ice pack with the lunch.
Children's lunch boxes do not need to be refrigerated if they are stored with a frozen item and kept inside school bags, away from heat sources such as direct sunlight.
Adults should store lunches in a workplace fridge or a cooler bag.
Where possible, lunches should contain low-risk foods including hard cheeses, well-cooked meats and poultry. Fresh, well-washed fruits and vegetables, and sandwich spreads such as honey and vegemite are ideal.
Lunch boxes and reusable drink bottles should be thoroughly washed and dried before they are used again. If they are damaged, the boxes should be replaced as bugs will grow in any cracks, the council says.
Food poisoning results, on average, in 120 deaths, 1.2 million visits to doctors, 300,000 prescriptions for antibiotics, and 2.1 billion days of lost work each year. The estimated annual cost of food poisoning in Australia is $1.2 billion.
SOURCE
Tens of thousands of woman could suffer a rare cancer caused by a banned drug taken by their mothers or even grandmothers. The drug, Diethylstilboestrol (DES), was freely prescribed to pregnant women in Britain for three decades up to 1973, and was supposed to prevent miscarriages.
But it was belatedly banned in Britain after it was found to increase the risk of miscarriage – and it is now feared that it can lead to a deadly cancer to a second and even third generation.
Some 2,000 women have already sought compensation in America, with payouts totalling up to £1bn from the numerous drug companies that sold DES, while scores more are launching more legal action.
Now fresh compensation cases are set to begin here, with tens of thousands of British women to be asked if they could be potential victims of the drug nicknamed ‘the silent Thalidomide’.
As well as causing a rare cervical and vaginal cancer, and possibly breast cancer, in the daughters, and potentially grandchildren, of the women who took it long ago, DES is also being blamed for causing fertility problems.
The drug, a synthetic copy of the female hormone oestrogen, was created in Britain in 1938, and was soon being prescribed to millions of women around the world.
Doubts about the wisdom of using it surfaced in 1953, when an American study showed it caused more, rather than fewer miscarriages.
But it was not until 1971 that US authorities told doctors to stop prescribing it - after it was found that one in a thousand of the daughters of women prescribed DES had developed the cervical and vaginal cancer ‘clear cell adenocarcinoma’ (CCAC). And it was only in 1973 that British doctors were advised to stop prescribing the drug.
The Royal College of Obstetrics and Gynaecology has suggested 7,500 British women took DES, but there are other claims that up to 300,000 could be at risk.
Figures suggest that daughters of women who took the drug are made 40 times more likely to develop the cancer CCAC, often when young adults. The cancer is fatal in more than a quarter of cases. One study suggested that breast cancer risk is also doubled.
It will be impossible for many possible victims to find out, of course, whether their mothers or grandmothers used the drug.
Research on rodents has lent weight to the fear that DES dangerously alters DNA not only in the individual taking the drug, but also that those changes are passed on at least two generations.
Washington DC lawyer Aaron Devine, who is representing the 80 American women currently seeking compensation, is due in Britain in a fortnight to arrange a search for potential victims here.
The first woman in Britain found to have suffered as a result of DES taken by her mother is Heather Justice, 59, of Jarrow in Tyne and Wear. She was diagnosed with vaginal cancer aged 25, then went through a hysterectomy and other surgery. Records showed her mother had taken DES in the 1950s, but because she did not know which company produced it, has been unable to bring legal action.
Mrs Justice said: ‘One of the problems is that unlike Thalidomide, where you see the problem the minute the baby was born, women who took DES had healthy babies. ‘Problems were hidden until the teens and twenties, by which point we were forgotten about. When I asked my mum what she had taken, she didn’t even remember the name of the stuff. It is a complete and utter minefield.’
Among others who believe they have been afflicted in Britain are Janet Hall, 61, of Bournemouth - whose mother died from lung cancer aged 32 – who had to have much of her cervix removed when she was 20. She suffered a miscarriage, then had two daughters. One, Hannah, 26, has had pre-cancerous cells found in her cervix, she said. Mrs Hall said: ‘I feel guilty for my girls. It messes with your mind; it makes you ask why you had to have children.’
A spokesman for the Department of Health spoke of having ‘every sympathy’ for self-proclaimed victims, but said: ‘With regard to compensation for people who believe they have been adversely affected by this drug, this is a matter for the manufacturer(s) and/or the UK licensees of the drug.’
SOURCE
Packed lunches now "incorrect"
I took a packed lunch to school every day as a kid living in the tropics and came to no harm, nor did any other kid that I knew of.
SCHOOL children and workers who leave home with a packed lunch are at risk of food poisoning in warm weather, health experts say.
Four in five Australian workers take packed lunches, of which only half are kept cool, a Newspoll survey has found.
With bacteria growing quickly in warm weather, the likelihood of food poisoning is high, especially when cold meat, soft cheeses, pates and raw-egg mayonnaise are on the menu, the Food Safety Information Council says.
The risk is reduced by packing a frozen juice box, water bottle or ice pack with the lunch.
Children's lunch boxes do not need to be refrigerated if they are stored with a frozen item and kept inside school bags, away from heat sources such as direct sunlight.
Adults should store lunches in a workplace fridge or a cooler bag.
Where possible, lunches should contain low-risk foods including hard cheeses, well-cooked meats and poultry. Fresh, well-washed fruits and vegetables, and sandwich spreads such as honey and vegemite are ideal.
Lunch boxes and reusable drink bottles should be thoroughly washed and dried before they are used again. If they are damaged, the boxes should be replaced as bugs will grow in any cracks, the council says.
Food poisoning results, on average, in 120 deaths, 1.2 million visits to doctors, 300,000 prescriptions for antibiotics, and 2.1 billion days of lost work each year. The estimated annual cost of food poisoning in Australia is $1.2 billion.
SOURCE
Tuesday, January 24, 2012
British insanity: Local councils will be handed £5bn to combat obesity
And it won't make a scrap of difference. It never does. Even when people do lose weight, they eventually put it back on -- and more
Local government is to take back responsibility for public health for the first time since the 1970s and will be given more than £5billion a year to stem obesity, binge drinking and smoking.
Powerful new public health directors based in councils will be asked to transform the NHS so it focuses much more on preventing illness rather than dealing with its consequences.
Announcing the plans today, Health Secretary Andrew Lansley will argue that a decade of failure has seen obesity rates spiral – with more than a quarter of adults now dangerously overweight – sexually transmitted infections double and gaps in life expectancy between rich and poor areas persist.
Mr Lansley, who aims to create a new ‘public health service’, will say that under Labour, public health was seen as ‘something to be sidelined’.
He will announce that next year £5.2billion will be spent on public health as responsibility is returned to local authorities for the first time since 1974. In a speech to health professionals, he will also pledge that the Government will increase health spending in real terms each year after that.
From April 2013, for the first time the funding will be ringfenced, meaning public health cash can no longer be raided to bail out other parts of the system.
Public health is currently the responsibility of primary care trusts. But as these will be scrapped with the introduction of GP consortiums in 2013, it has been decided that it should revert back to local government – which is responsible for wider determinants of health, such as housing, transport and leisure.
Local government will devise its own schemes for promoting public health, though ministers favour ‘nudging’ people to make healthy choices by presenting them as social norms rather than Labour’s ‘nanny state’ approach.
One example was the use of signs in shops saying ‘most people who shop here buy at least two pieces of fruit’, a tactic which proved effective in trials.
Under the new system, local authorities will be judged against a wide range of measures including tooth decay in children and reducing the number of falls in older people, and wider factors such as school attendance, domestic abuse, homelessness and air pollution. There will also be a major push to promote breastfeeding.
Mr Lansley will say: ‘The job of the Government – and my responsibility – is to help people live healthier lives.
‘The framework is about giving local authorities the ability to focus on the most effective ways to improve the public’s health and reduce health inequalities, long-term, from cradle to grave. Moving away from an old-style, top-down, target-driven regime, and towards outcomes that we all want to see.
‘Some are straightforward and obvious. Others are more complex, maybe things you wouldn’t immediately think of. ‘But they all help us live longer, healthier lives, and improve the health of the poorest, fastest.
He will also point out that ‘2000 to 2010 was a decade in which public health was seen as relatively unimportant, something to be sidelined’.
He will say: ‘Obesity rates from 2000 to 2010 rose from 21.2 per cent to 26.1 per cent so now over a quarter of adults are obese; sexually-transmitted infections, after the steep declines in the Eighties to Nineties, doubled in the subsequent decade; and health inequalities persist, with gaps in life expectancy of over a decade between people born in the richest areas and people born in the poorest.’
Mr Lansley will cite last year’s National Audit Office report which was unable to conclude that the £20billion Labour spent on reducing health inequalities was good value for money.
Councils who succeed will be rewarded with a ‘health premium bonus’ to spend on public health in the following year.
‘I want local government to be bold,’ Mr Lansley will say. ‘Really push to make things better. The health premium will encourage that, rewarding local authorities that make a real, demonstrable difference.’
SOURCE
'Breast is best advice is too posh': Charity stops promoting it in ante-natal classes
A leading childbirth charity will stop telling mothers to breastfeed over fears its image is ‘too posh’.
The National Childbirth Trust will no longer promote the practice to all women in its ante-natal classes. Instead it will encourage those who have already decided to take it up to do it properly.
The change follows concerns that its ‘breastapo’ tactics are alienating some women reluctant to breastfeed, particularly among the working class. The charity wants women from more diverse backgrounds to attend its classes.
The NHS recommends that babies are breastfed exclusively for six months. Breastfeeding rates range from 90 per cent for more affluent women, to just over 70 per cent for those in the poorest social classes and only 63 per cent for teenage mothers.
It provided ante-natal classes for about 90,000 couples last year, 16 per cent of them free through the NHS. But it has been criticised for alienating women who decide not to breastfeed or those who chose to have a caesarean.
Last year TV presenter Kirstie Allsopp claimed that she and thousands of mothers were being made to feel a ‘failure’ for having c-sections.
Spokesman Anne Fox said: ‘We need to get the message out that the NCT is for everyone, not just for “posh” parents as some people assume. ‘We want to have a more diverse reach. We have always worked on word of mouth, but now we want the person who says “You should go to NCT” to be a pregnant 15-year-old in central Manchester. ‘Our practitioners and volunteers are training to support all parents; those from ethnic minority groups, families that are newly arrived and those who parent on their own.’
The NCT, formed in 1956, has 100,000 members, making it the biggest parenting charity in the country.
SOURCE
And it won't make a scrap of difference. It never does. Even when people do lose weight, they eventually put it back on -- and more
Local government is to take back responsibility for public health for the first time since the 1970s and will be given more than £5billion a year to stem obesity, binge drinking and smoking.
Powerful new public health directors based in councils will be asked to transform the NHS so it focuses much more on preventing illness rather than dealing with its consequences.
Announcing the plans today, Health Secretary Andrew Lansley will argue that a decade of failure has seen obesity rates spiral – with more than a quarter of adults now dangerously overweight – sexually transmitted infections double and gaps in life expectancy between rich and poor areas persist.
Mr Lansley, who aims to create a new ‘public health service’, will say that under Labour, public health was seen as ‘something to be sidelined’.
He will announce that next year £5.2billion will be spent on public health as responsibility is returned to local authorities for the first time since 1974. In a speech to health professionals, he will also pledge that the Government will increase health spending in real terms each year after that.
From April 2013, for the first time the funding will be ringfenced, meaning public health cash can no longer be raided to bail out other parts of the system.
Public health is currently the responsibility of primary care trusts. But as these will be scrapped with the introduction of GP consortiums in 2013, it has been decided that it should revert back to local government – which is responsible for wider determinants of health, such as housing, transport and leisure.
Local government will devise its own schemes for promoting public health, though ministers favour ‘nudging’ people to make healthy choices by presenting them as social norms rather than Labour’s ‘nanny state’ approach.
One example was the use of signs in shops saying ‘most people who shop here buy at least two pieces of fruit’, a tactic which proved effective in trials.
Under the new system, local authorities will be judged against a wide range of measures including tooth decay in children and reducing the number of falls in older people, and wider factors such as school attendance, domestic abuse, homelessness and air pollution. There will also be a major push to promote breastfeeding.
Mr Lansley will say: ‘The job of the Government – and my responsibility – is to help people live healthier lives.
‘The framework is about giving local authorities the ability to focus on the most effective ways to improve the public’s health and reduce health inequalities, long-term, from cradle to grave. Moving away from an old-style, top-down, target-driven regime, and towards outcomes that we all want to see.
‘Some are straightforward and obvious. Others are more complex, maybe things you wouldn’t immediately think of. ‘But they all help us live longer, healthier lives, and improve the health of the poorest, fastest.
He will also point out that ‘2000 to 2010 was a decade in which public health was seen as relatively unimportant, something to be sidelined’.
He will say: ‘Obesity rates from 2000 to 2010 rose from 21.2 per cent to 26.1 per cent so now over a quarter of adults are obese; sexually-transmitted infections, after the steep declines in the Eighties to Nineties, doubled in the subsequent decade; and health inequalities persist, with gaps in life expectancy of over a decade between people born in the richest areas and people born in the poorest.’
Mr Lansley will cite last year’s National Audit Office report which was unable to conclude that the £20billion Labour spent on reducing health inequalities was good value for money.
Councils who succeed will be rewarded with a ‘health premium bonus’ to spend on public health in the following year.
‘I want local government to be bold,’ Mr Lansley will say. ‘Really push to make things better. The health premium will encourage that, rewarding local authorities that make a real, demonstrable difference.’
SOURCE
'Breast is best advice is too posh': Charity stops promoting it in ante-natal classes
A leading childbirth charity will stop telling mothers to breastfeed over fears its image is ‘too posh’.
The National Childbirth Trust will no longer promote the practice to all women in its ante-natal classes. Instead it will encourage those who have already decided to take it up to do it properly.
The change follows concerns that its ‘breastapo’ tactics are alienating some women reluctant to breastfeed, particularly among the working class. The charity wants women from more diverse backgrounds to attend its classes.
The NHS recommends that babies are breastfed exclusively for six months. Breastfeeding rates range from 90 per cent for more affluent women, to just over 70 per cent for those in the poorest social classes and only 63 per cent for teenage mothers.
It provided ante-natal classes for about 90,000 couples last year, 16 per cent of them free through the NHS. But it has been criticised for alienating women who decide not to breastfeed or those who chose to have a caesarean.
Last year TV presenter Kirstie Allsopp claimed that she and thousands of mothers were being made to feel a ‘failure’ for having c-sections.
Spokesman Anne Fox said: ‘We need to get the message out that the NCT is for everyone, not just for “posh” parents as some people assume. ‘We want to have a more diverse reach. We have always worked on word of mouth, but now we want the person who says “You should go to NCT” to be a pregnant 15-year-old in central Manchester. ‘Our practitioners and volunteers are training to support all parents; those from ethnic minority groups, families that are newly arrived and those who parent on their own.’
The NCT, formed in 1956, has 100,000 members, making it the biggest parenting charity in the country.
SOURCE
Monday, January 23, 2012
A most interesting finding
Contrary to expectations, babies born into difficult family situations adapt to that by developing faster. And their experience in utero primes them to do that, allegedly.
I wonder, however, are we looking at a type of chimpanzee effect here. That effect connects early maturation to lower final levels of mental ability. If the "depressed" mothers in the study were of sub-par average IQ, we would expect their infants to mature faster anyhow -- with no fetal detection involved. Control for maternal IQ would resolve that
Prescient Human Fetuses Thrive
Curt A. Sandman et al.
Abstract
Fetal detection of adversity is a conserved trait that allows many species to adapt their early developmental trajectories to ensure survival. According to the fetal-programming model, exposure to stressful or hostile conditions in utero is associated with compromised development and a lifelong risk of adverse health outcomes.
In a longitudinal study, we examined the consequences of prenatal and postnatal exposure to adversity for infant development. We found increased motor and mental development during the 1st year of life among infants whose mothers experienced congruent levels of depressive symptoms during and after pregnancy, even when the levels of symptoms were relatively high and the prenatal and postnatal environments were unfavorable.
Congruence between prenatal and postnatal environments prepares the fetus for postnatal life and confers an adaptive advantage for critical survival functions during early development.
SOURCE
Tanning addicts snap up banned drug Melanotan II
Just another drug of abuse that probably would be better legalized so its effects can be properly tracked and users helped where needed
HEALTH experts are alarmed at a booming trade in an artificial tanning drug that promises to make you "tanned, thin and turned on".
Melanotan II, nicknamed the "Barbie Drug", is banned from commercial sale in Australia but tan-addicts are snapping up vials of the injectable drug over the internet. Initially popular with bodybuilders, the drug is now being used by models, brides-to-be, actresses and others seeking an instant tan.
One online distributor Pure Peptides, listed as being based in Australia and the US, claims it was flooded with more than 10,000 orders in the past year.
A 10mg vial of the synthetic hormone which increases the levels of melanin, the skin's darker pigment can be bought online for as little as $40.
But the Australian Medical Association warns it could cost users their lives. "People should not be messing with something that's unproven and theoretically increases the risk of skin cancers, particularly melanomas," Queensland president Dr Richard Kidd said.
The drug has also been banned in Britain, Canada and throughout Europe after reported side effects including nausea, flushing, the darkening of freckles, high-blood pressure, physical scarring, suppressed appetite, spontaneous erections and increased libido.
Dr Kidd said: "There hasn't been any proper clinical studies done on humans. They're putting dollars before lives."
Melanotan II is banned from commercial sale and the Therapeutic Goods Administration last year made it illegal for Australians to buy it from overseas for personal use without a prescription.
But the move has not stemmed the tide of sales, with the drug still freely promoted and available online to Australians.
A TGA spokeswoman said: "It continues to be unlawful for Melanotan to be imported and sold on a commercial basis. In addition, it is now unlawful to import Melanotan for personal use unless the substance is prescribed by a medical practitioner registered in Australia."
One supplier Pure Melanotan declares on its website: "All Australian orders are shipped from our local Australian distribution center via Australian Post Express, No Customs & No Duties or fees."
The TGA said they were not aware of these local warehouses but warned the supply of the drug in Australia could be an offence against state and Commonwealth legislation. The TGA said it would investigate if the drug was slipping into Australia unchecked.
But Dr Kidd warns Melanotan II is unapproved for a good reason: "You might end up accidentally killing yourself."
SOURCE
Contrary to expectations, babies born into difficult family situations adapt to that by developing faster. And their experience in utero primes them to do that, allegedly.
I wonder, however, are we looking at a type of chimpanzee effect here. That effect connects early maturation to lower final levels of mental ability. If the "depressed" mothers in the study were of sub-par average IQ, we would expect their infants to mature faster anyhow -- with no fetal detection involved. Control for maternal IQ would resolve that
Prescient Human Fetuses Thrive
Curt A. Sandman et al.
Abstract
Fetal detection of adversity is a conserved trait that allows many species to adapt their early developmental trajectories to ensure survival. According to the fetal-programming model, exposure to stressful or hostile conditions in utero is associated with compromised development and a lifelong risk of adverse health outcomes.
In a longitudinal study, we examined the consequences of prenatal and postnatal exposure to adversity for infant development. We found increased motor and mental development during the 1st year of life among infants whose mothers experienced congruent levels of depressive symptoms during and after pregnancy, even when the levels of symptoms were relatively high and the prenatal and postnatal environments were unfavorable.
Congruence between prenatal and postnatal environments prepares the fetus for postnatal life and confers an adaptive advantage for critical survival functions during early development.
SOURCE
Tanning addicts snap up banned drug Melanotan II
Just another drug of abuse that probably would be better legalized so its effects can be properly tracked and users helped where needed
HEALTH experts are alarmed at a booming trade in an artificial tanning drug that promises to make you "tanned, thin and turned on".
Melanotan II, nicknamed the "Barbie Drug", is banned from commercial sale in Australia but tan-addicts are snapping up vials of the injectable drug over the internet. Initially popular with bodybuilders, the drug is now being used by models, brides-to-be, actresses and others seeking an instant tan.
One online distributor Pure Peptides, listed as being based in Australia and the US, claims it was flooded with more than 10,000 orders in the past year.
A 10mg vial of the synthetic hormone which increases the levels of melanin, the skin's darker pigment can be bought online for as little as $40.
But the Australian Medical Association warns it could cost users their lives. "People should not be messing with something that's unproven and theoretically increases the risk of skin cancers, particularly melanomas," Queensland president Dr Richard Kidd said.
The drug has also been banned in Britain, Canada and throughout Europe after reported side effects including nausea, flushing, the darkening of freckles, high-blood pressure, physical scarring, suppressed appetite, spontaneous erections and increased libido.
Dr Kidd said: "There hasn't been any proper clinical studies done on humans. They're putting dollars before lives."
Melanotan II is banned from commercial sale and the Therapeutic Goods Administration last year made it illegal for Australians to buy it from overseas for personal use without a prescription.
But the move has not stemmed the tide of sales, with the drug still freely promoted and available online to Australians.
A TGA spokeswoman said: "It continues to be unlawful for Melanotan to be imported and sold on a commercial basis. In addition, it is now unlawful to import Melanotan for personal use unless the substance is prescribed by a medical practitioner registered in Australia."
One supplier Pure Melanotan declares on its website: "All Australian orders are shipped from our local Australian distribution center via Australian Post Express, No Customs & No Duties or fees."
The TGA said they were not aware of these local warehouses but warned the supply of the drug in Australia could be an offence against state and Commonwealth legislation. The TGA said it would investigate if the drug was slipping into Australia unchecked.
But Dr Kidd warns Melanotan II is unapproved for a good reason: "You might end up accidentally killing yourself."
SOURCE
Sunday, January 22, 2012
Are dads to blame for unhealthy kids? New study shows obese fathers more likely to have overweight children
It's what you would expect from genetics. Everything else is a minor influence
New research has linked fathers' weights to their childrens' - finding that an obese man is more likely to have obese children.
The Australian study, published in the International Journal of Obesity, looked at the weights of eight- and nine-year-old children from two-parent families where one parent was obese.
The report found that 'having an overweight or obese father, but a healthy weight mother, significantly increased the odds of child obesity', while the reverse did not hold true.
The findings go against popularly held beliefs that mothers - who tend to spend more time with children than fathers as well as usually controlling food shopping and meals - have more influence over children's weight.
Today Mums says that scientists had before theorised that the sex of offspring was an important factor when it came to parents' sizes affecting obesity.
It was thought that obese mums were more likely to have obese daughters and obese fathers would similarly be more likely to have obese sons. The new evidence throws that into doubt.
The counter-intuitive results, yielded from 3,825 children, have surprised the University of Newcastle, NSW, scientists, who have not yet isolated the reasons for the correlation.
In an email to Today Mums, study co-author Emily Freeman, from the university's Family Action Centre, said that the results merited prompt action: 'We felt that it was very important to get the message out there straight away that dads have a big role in keeping their children healthy'.
The health scientist went on to say that a father's position as a role model may be influencing children's weights.
A dad who eats his greens and heads to the park for exercise is undoubtedly setting a good example - and one that is corroborated by anecdotal evidence when it comes to healthy children, says the scientist.
SOURCE
Men over 6ft 'face a 24% lower risk of heart failure'
This is consistent with there being a general syndrome of biological fitness. High IQ people tend to be taller and healthier so we are seeing another part of that below
They are said to be more desirable to women, more successful and more likely to father children. And now scientists claim that tall men have yet another advantage – they are less at risk of heart problems.
Harvard researchers have found that those who are more than 6ft are a quarter less likely to suffer from heart failure than men just a few inches smaller.
They looked at the records of 22,000 male doctors in their mid-fifties who were subsequently followed over a 22-year period. They each filled in an initial questionnaire on their height, weight and general health and then every year subsequently filled in surveys about any new medical diagnoses.
The study, published in the American Journal of Cardiology, found that 1,444 men developed heart failure which was about 7 per cent of the total. But men who were 6ft or over (1.8 meters) were 24 per cent less likely to report having heart failure than those who were 5ft 8 or smaller (1.72 meters).
This was after their age and weight, as well as whether they had high blood pressure and diabetes, had all been taken into account.
The scientists think that one reason is that shorter men may have had childhood diseases that stunted their growth. In adulthood this could have led to the build-up of plaque in their arteries and higher blood pressure.
But they also think that the biology of taller men may put them at less risk. They say that there is greater distance between certain points in their arteries and their hearts which puts the heart under less strain.
Jeffrey Teuteberg, a cardiologist at the University of Pittsburgh Medical Center who was not involved in the study said: 'As much as we know about the development of very common diseases like heart failure, there’s still a lot we don’t know. “There’s still a lot more that impacts the development of those diseases beyond those things,” 'The message certainly shouldn’t be: "If you’re tall, don’t worry about these sorts of things, or if you’re short, you’re doomed."'
Heart failure affects around 900,000 people in Britain, mainly the elderly.
It occurs when their hearts are too weak to properly pump blood around the body and can be caused by heart attacks, which cause the organ to weaken.
SOURCE
It's what you would expect from genetics. Everything else is a minor influence
New research has linked fathers' weights to their childrens' - finding that an obese man is more likely to have obese children.
The Australian study, published in the International Journal of Obesity, looked at the weights of eight- and nine-year-old children from two-parent families where one parent was obese.
The report found that 'having an overweight or obese father, but a healthy weight mother, significantly increased the odds of child obesity', while the reverse did not hold true.
The findings go against popularly held beliefs that mothers - who tend to spend more time with children than fathers as well as usually controlling food shopping and meals - have more influence over children's weight.
Today Mums says that scientists had before theorised that the sex of offspring was an important factor when it came to parents' sizes affecting obesity.
It was thought that obese mums were more likely to have obese daughters and obese fathers would similarly be more likely to have obese sons. The new evidence throws that into doubt.
The counter-intuitive results, yielded from 3,825 children, have surprised the University of Newcastle, NSW, scientists, who have not yet isolated the reasons for the correlation.
In an email to Today Mums, study co-author Emily Freeman, from the university's Family Action Centre, said that the results merited prompt action: 'We felt that it was very important to get the message out there straight away that dads have a big role in keeping their children healthy'.
The health scientist went on to say that a father's position as a role model may be influencing children's weights.
A dad who eats his greens and heads to the park for exercise is undoubtedly setting a good example - and one that is corroborated by anecdotal evidence when it comes to healthy children, says the scientist.
SOURCE
Men over 6ft 'face a 24% lower risk of heart failure'
This is consistent with there being a general syndrome of biological fitness. High IQ people tend to be taller and healthier so we are seeing another part of that below
They are said to be more desirable to women, more successful and more likely to father children. And now scientists claim that tall men have yet another advantage – they are less at risk of heart problems.
Harvard researchers have found that those who are more than 6ft are a quarter less likely to suffer from heart failure than men just a few inches smaller.
They looked at the records of 22,000 male doctors in their mid-fifties who were subsequently followed over a 22-year period. They each filled in an initial questionnaire on their height, weight and general health and then every year subsequently filled in surveys about any new medical diagnoses.
The study, published in the American Journal of Cardiology, found that 1,444 men developed heart failure which was about 7 per cent of the total. But men who were 6ft or over (1.8 meters) were 24 per cent less likely to report having heart failure than those who were 5ft 8 or smaller (1.72 meters).
This was after their age and weight, as well as whether they had high blood pressure and diabetes, had all been taken into account.
The scientists think that one reason is that shorter men may have had childhood diseases that stunted their growth. In adulthood this could have led to the build-up of plaque in their arteries and higher blood pressure.
But they also think that the biology of taller men may put them at less risk. They say that there is greater distance between certain points in their arteries and their hearts which puts the heart under less strain.
Jeffrey Teuteberg, a cardiologist at the University of Pittsburgh Medical Center who was not involved in the study said: 'As much as we know about the development of very common diseases like heart failure, there’s still a lot we don’t know. “There’s still a lot more that impacts the development of those diseases beyond those things,” 'The message certainly shouldn’t be: "If you’re tall, don’t worry about these sorts of things, or if you’re short, you’re doomed."'
Heart failure affects around 900,000 people in Britain, mainly the elderly.
It occurs when their hearts are too weak to properly pump blood around the body and can be caused by heart attacks, which cause the organ to weaken.
SOURCE
Saturday, January 21, 2012
Patients With Normal Bone Density Can Delay Retests, Study Suggests
Bone loss and osteoporosis develop so slowly in most women whose bones test normal at age 65 that many can safely wait as long as 15 years before having a second bone density test, researchers report in a new study.
The study, published in Thursday’s issue of The New England Journal of Medicine, is part of a broad rethinking of how to diagnose and treat the potentially debilitating bone disease that can lead to broken hips and collapsing spines.
A class of drugs, bisphosphonates, which includes Fosamax, has been found to prevent fractures in people with osteoporosis. But medical experts no longer recommend the medicines to prevent osteoporosis itself. They no longer want women to take them indefinitely, and no longer consider bone density measurements the sole defining factor in deciding if a woman needs to be treated.
Now, with the new study, researchers are asking whether frequent bone density measurements even make sense for the majority of older women whose bone density is not near a danger zone on initial tests, recommended at age 65.
“Bone density testing has been oversold,” said Steven Cummings, the study’s principal investigator and an emeritus professor of medical epidemiology and biostatistics at the University of California, San Francisco.
The study followed nearly 5,000 women ages 67 and older for more than a decade. The women had a bone density test when they entered the study and did not have osteoporosis. (In a separate national study by the Centers for Disease Control and Prevention, about 70 percent of women over age 65 did not have osteoporosis.)
The researchers report that fewer than 1 percent of women with normal bone density when they entered the study, and fewer than 5 percent with mildly low bone density, developed osteoporosis in the ensuing 15 years. But of those with substantially low bone density at the study’s start, close to the cutoff point for osteoporosis of fewer than 2.5 standard deviations from the reference level, 10 percent progressed to osteoporosis in about a year.
Dr. Margaret Gourlay, the study’s lead author and a family practice specialist and osteoporosis researcher at the University of North Carolina, said she and her colleagues were surprised by how slowly osteoporosis progressed in women.
Medicare pays for a bone density test every two years and many doctors have assumed that is the ideal interval, although national guidelines recommend them only at “regular intervals.”
“I think this will change the way doctors think about screening,” Dr. Gourlay said.
The results, said Joan A. McGowan, director of the division of musculoskeletal diseases at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, “provide telling evidence that you are not going to fall off a cliff if you have normal bone density in your 60s or early 70s, that you are not going to have osteoporosis in the next five years unless something else happens.”
For example, said Dr. McGowan, who was not involved in the study, a woman who had to take high doses of corticosteroids for another medical condition would lose bone rapidly. But the findings “cover most normal women,” she said.
Bone density screening took off after Fosamax, the first bisphosphonate, was approved at the end of 1995. For the first time, doctors had a specific treatment that had been shown to prevent fractures in people with osteoporosis.
For years doctors were overly enthusiastic, prescribing it for women whose bone density was lower than normal but not in a danger zone, keeping women on the drug indefinitely. They even gave a name, osteopenia, to lower than normal bone density, although it was not clear it had real clinical significance.
Now, osteoporosis experts consider osteopenia to be a risk factor, not a disease, and its importance varies depending on a patient’s age, said Dr. Ethel S. Siris, an osteoporosis researcher at Columbia University who was not involved in the study.
Doctors are more likely to prescribe bisphosphonates for older patients and recommend against them for most younger postmenopausal women with osteopenia.
The experts also generally recommend that most people on bisphosphonates take them for just five years at a time, followed by a drug holiday of undetermined length. The idea is to reduce the risk of rare but serious side effects, including unusual thighbone fractures and loss of bone in the jaw.
A risk calculator, FRAX, can help determine whether treatment is recommended. It assesses a combination of risk factors: whether a parent has had a hip fracture, the age of the patient, steroid use, bone density at the hip, and whether the person has broken a bone after age 50, an especially important indicator. Nearly half who break a hip already had already broken another bone, Dr. Siris said.
“If you are an older individual, a man or a woman, who already broke a major bone — spine, hip, shoulder, or pelvis or wrist — take it very seriously and get treated,” she said. “If you have relatively good bone density then you are not at risk now.”
SOURCE
The Report on Carcinogens
What Went Wrong and What Can Be Done to Fix It
There is nothing wrong in principle with publishing periodic reports identifying substances that pose carcinogenic risks to humans. Cancer remains a serious disease even though advances in diagnosis and treatment have rendered most types much less often fatal than they were when President Richard Nixon declared the “war on cancer” in 1971. But it would be a mistake to continue basing these reports on scientific knowledge and primitive technology dating from the 1960s.
The National Toxicology Program’s (NTP) Report on Carcinogens (RoC) is one such periodic report. The NTP has interpreted its statutory charge in a way that never was consistent with the law authorizing its preparation, resulting in Reports that never could live up to Congress’ original intent. Though the law requires the NTP to estimate the number of Americans actually exposed, and to list substances only if a significant number of Americans are exposed to them, the NTP functionally ignores exposure. The law also requires the NTP to estimate the reduction in cancer incidence resulting from regulatory standards, but it does not perform that required task, either.
Problems with the RoC begin with the NTP’s listing criteria. A careful review of the text shows that they are mere tautologies. For example, a substance is deemed to be a known carcinogen if the NTP decides that the evidence from human studies is sufficient. The minimum threshold for designation as a known carcinogen is unknown to the public because the NTP never says what is required for evidence to be sufficient. Thus, a substance is a known human carcinogen if the NTP says the evidence is sufficient. Conversely, the evidence is sufficient if the NTP says the substance is a known carcinogen. Similarly circular logic pervades the definition of a reasonably anticipated human carcinogen.
Worse, the NTP appears to be institutionally incapable of incorporating decades of advancements in scientific knowledge into its listing decisions, and there is no transparent way to scientifically rebut or reverse a listing decision once it has been made.
Both of the statutory categories for assignment (known and reasonably anticipated) imply that a causal relationship has been demonstrated with near certainty in the first case, and with an unspecified but lesser confidence level in the second. But the NTP’s listing criteria do not require any demonstration of causality. Rather, the NTP assumes that causality is demonstrated when it decides to list. This is clear from the grammatical structure of the criteria, which treats causality as a merely parenthetical element.
This enables the NTP to reserve to itself the discretion to consider whatever information it wants, to exclude whatever information it wants, and to evaluate that information in accordance with whatever ad hoc criteria it wants to apply. The NTP does not constrain itself to scientific information, either. By withholding B. 2 Belzer: The Report on Carcinogens from the public the weight of evidence scheme, the NTP preserves the policy discretion to give any weight it wants to policy goals and objectives, and to keep those weights hidden from public view.
This paper concludes with specific recommendations for statutory reforms that would improve the scientific quality of listing decisions and the practical utility of the RoC for screening-level risk-benefit decision-making. Each recommendation would help restore science to its intended role and end the NTP’s science charade.
SOURCE
Bone loss and osteoporosis develop so slowly in most women whose bones test normal at age 65 that many can safely wait as long as 15 years before having a second bone density test, researchers report in a new study.
The study, published in Thursday’s issue of The New England Journal of Medicine, is part of a broad rethinking of how to diagnose and treat the potentially debilitating bone disease that can lead to broken hips and collapsing spines.
A class of drugs, bisphosphonates, which includes Fosamax, has been found to prevent fractures in people with osteoporosis. But medical experts no longer recommend the medicines to prevent osteoporosis itself. They no longer want women to take them indefinitely, and no longer consider bone density measurements the sole defining factor in deciding if a woman needs to be treated.
Now, with the new study, researchers are asking whether frequent bone density measurements even make sense for the majority of older women whose bone density is not near a danger zone on initial tests, recommended at age 65.
“Bone density testing has been oversold,” said Steven Cummings, the study’s principal investigator and an emeritus professor of medical epidemiology and biostatistics at the University of California, San Francisco.
The study followed nearly 5,000 women ages 67 and older for more than a decade. The women had a bone density test when they entered the study and did not have osteoporosis. (In a separate national study by the Centers for Disease Control and Prevention, about 70 percent of women over age 65 did not have osteoporosis.)
The researchers report that fewer than 1 percent of women with normal bone density when they entered the study, and fewer than 5 percent with mildly low bone density, developed osteoporosis in the ensuing 15 years. But of those with substantially low bone density at the study’s start, close to the cutoff point for osteoporosis of fewer than 2.5 standard deviations from the reference level, 10 percent progressed to osteoporosis in about a year.
Dr. Margaret Gourlay, the study’s lead author and a family practice specialist and osteoporosis researcher at the University of North Carolina, said she and her colleagues were surprised by how slowly osteoporosis progressed in women.
Medicare pays for a bone density test every two years and many doctors have assumed that is the ideal interval, although national guidelines recommend them only at “regular intervals.”
“I think this will change the way doctors think about screening,” Dr. Gourlay said.
The results, said Joan A. McGowan, director of the division of musculoskeletal diseases at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, “provide telling evidence that you are not going to fall off a cliff if you have normal bone density in your 60s or early 70s, that you are not going to have osteoporosis in the next five years unless something else happens.”
For example, said Dr. McGowan, who was not involved in the study, a woman who had to take high doses of corticosteroids for another medical condition would lose bone rapidly. But the findings “cover most normal women,” she said.
Bone density screening took off after Fosamax, the first bisphosphonate, was approved at the end of 1995. For the first time, doctors had a specific treatment that had been shown to prevent fractures in people with osteoporosis.
For years doctors were overly enthusiastic, prescribing it for women whose bone density was lower than normal but not in a danger zone, keeping women on the drug indefinitely. They even gave a name, osteopenia, to lower than normal bone density, although it was not clear it had real clinical significance.
Now, osteoporosis experts consider osteopenia to be a risk factor, not a disease, and its importance varies depending on a patient’s age, said Dr. Ethel S. Siris, an osteoporosis researcher at Columbia University who was not involved in the study.
Doctors are more likely to prescribe bisphosphonates for older patients and recommend against them for most younger postmenopausal women with osteopenia.
The experts also generally recommend that most people on bisphosphonates take them for just five years at a time, followed by a drug holiday of undetermined length. The idea is to reduce the risk of rare but serious side effects, including unusual thighbone fractures and loss of bone in the jaw.
A risk calculator, FRAX, can help determine whether treatment is recommended. It assesses a combination of risk factors: whether a parent has had a hip fracture, the age of the patient, steroid use, bone density at the hip, and whether the person has broken a bone after age 50, an especially important indicator. Nearly half who break a hip already had already broken another bone, Dr. Siris said.
“If you are an older individual, a man or a woman, who already broke a major bone — spine, hip, shoulder, or pelvis or wrist — take it very seriously and get treated,” she said. “If you have relatively good bone density then you are not at risk now.”
SOURCE
The Report on Carcinogens
What Went Wrong and What Can Be Done to Fix It
There is nothing wrong in principle with publishing periodic reports identifying substances that pose carcinogenic risks to humans. Cancer remains a serious disease even though advances in diagnosis and treatment have rendered most types much less often fatal than they were when President Richard Nixon declared the “war on cancer” in 1971. But it would be a mistake to continue basing these reports on scientific knowledge and primitive technology dating from the 1960s.
The National Toxicology Program’s (NTP) Report on Carcinogens (RoC) is one such periodic report. The NTP has interpreted its statutory charge in a way that never was consistent with the law authorizing its preparation, resulting in Reports that never could live up to Congress’ original intent. Though the law requires the NTP to estimate the number of Americans actually exposed, and to list substances only if a significant number of Americans are exposed to them, the NTP functionally ignores exposure. The law also requires the NTP to estimate the reduction in cancer incidence resulting from regulatory standards, but it does not perform that required task, either.
Problems with the RoC begin with the NTP’s listing criteria. A careful review of the text shows that they are mere tautologies. For example, a substance is deemed to be a known carcinogen if the NTP decides that the evidence from human studies is sufficient. The minimum threshold for designation as a known carcinogen is unknown to the public because the NTP never says what is required for evidence to be sufficient. Thus, a substance is a known human carcinogen if the NTP says the evidence is sufficient. Conversely, the evidence is sufficient if the NTP says the substance is a known carcinogen. Similarly circular logic pervades the definition of a reasonably anticipated human carcinogen.
Worse, the NTP appears to be institutionally incapable of incorporating decades of advancements in scientific knowledge into its listing decisions, and there is no transparent way to scientifically rebut or reverse a listing decision once it has been made.
Both of the statutory categories for assignment (known and reasonably anticipated) imply that a causal relationship has been demonstrated with near certainty in the first case, and with an unspecified but lesser confidence level in the second. But the NTP’s listing criteria do not require any demonstration of causality. Rather, the NTP assumes that causality is demonstrated when it decides to list. This is clear from the grammatical structure of the criteria, which treats causality as a merely parenthetical element.
This enables the NTP to reserve to itself the discretion to consider whatever information it wants, to exclude whatever information it wants, and to evaluate that information in accordance with whatever ad hoc criteria it wants to apply. The NTP does not constrain itself to scientific information, either. By withholding B. 2 Belzer: The Report on Carcinogens from the public the weight of evidence scheme, the NTP preserves the policy discretion to give any weight it wants to policy goals and objectives, and to keep those weights hidden from public view.
This paper concludes with specific recommendations for statutory reforms that would improve the scientific quality of listing decisions and the practical utility of the RoC for screening-level risk-benefit decision-making. Each recommendation would help restore science to its intended role and end the NTP’s science charade.
SOURCE
Friday, January 20, 2012
Weight gain linked to risk of aggressive cancer - study
The usual rubbish. They are most likely just picking up that poor people tend both to get fatter and to have poorer heath generally anyhow. Note that it is the moderately overweight who have the longest lifespans
THE risk of death from prostate cancer nearly doubles in men who have put on 20 kilograms or more in their adult life, new Australian research has found.
The paper, published in the International Journal of Cancer, shows an increase in body weight during a man's adult life is associated with an increased risk of suffering an aggressive form of prostate cancer and of dying from prostate cancer.
Having a high body mass throughout life was also associated with increased risk of aggressive prostate cancer. "This study and other similar studies have shown that obesity is related to aggressive and fatal cancer," said the study's co-author, Dallas English. "Maintaining a healthy weight during adult life is really the bottom line."
Professor English, director of the centre for molecular, environmental, genetic and analytic epidemiology at the University of Melbourne, said one of his concerns was that the study - of more than 17,000 Australian men aged 40 to 69 - drew participants from a generation in which childhood obesity was not a significant issue.
He said the higher rates of obesity among children now might worsen outcomes. "In Australia, things have changed a lot," he said. "We haven't had the experience of people growing up with childhood obesity."
SOURCE
Daily dose of rosehip extract could help cut heart disease by lowering blood pressure and cholesterol levels
The small changes observed may have no clinical significance. Journal article here
A daily dose of the herbal remedy rose hip could cut the risk of heart disease, new research shows. Obese patients who consumed a drink made with rose hip powder every day for just six weeks saw their blood pressure and cholesterol levels drop significantly.
The tiny berries, which sprout at the end of the rose-blooming season, have been used for centuries as a folk remedy for conditions like arthritis. They are packed with vitamin C and are thought to have powerful anti-inflammatory properties.
One study in 2007 showed patients with sore joints who took a rose hip capsule every day experienced a 40 per cent drop in pain levels and a 25 per cent improvement in mobility.
In the latest research, published in the European Journal of Clinical Nutrition, scientists at Lund University in Sweden recruited 31 obese men and women to see if a daily concoction made with rose hip powder would reduce their risks of developing type two diabetes and heart disease.
Each one spent six weeks drinking the rose hip solution, made with 40 grammes of rose hip powder, followed by six weeks on a drink make from apples and grapes.
At the end of each experiment, researchers measured patients’ body weight, blood pressure, blood fat levels and glucose tolerance - a test to see if they are in the early stages of diabetes.
After six weeks on the rose hip drink, patients saw their blood pressure drop an average of 3.4 per cent, a small but significant decline, and their total cholesterol levels drop by almost five per cent.
Further tests revealed a bigger drop - six per cent - in levels of LDL cholesterol, the ‘bad’ type of blood fat thought to heighten heart disease risks.
Scientists estimated that the drop in cholesterol and blood pressure combined would reduce the risk of heart disease in obese patients by 17 per cent.
And they said if further studies confirmed the cardiovascular benefits of the common garden berry, it could even be used as an alternative therapy for patients who are unable to take the anti-cholesterol drugs statins due to side effects.
In a report on their findings the researchers said: ‘The findings may have important health implications. They may represent an attractive alternative to statin treatment for people that, because of muscle pain and increases in liver and muscle enzymes, do not tolerate statins.
‘The same is true for people at risk of developing diabetes, as statins recently were shown to increase the risk of diabetes.’
SOURCE
The usual rubbish. They are most likely just picking up that poor people tend both to get fatter and to have poorer heath generally anyhow. Note that it is the moderately overweight who have the longest lifespans
THE risk of death from prostate cancer nearly doubles in men who have put on 20 kilograms or more in their adult life, new Australian research has found.
The paper, published in the International Journal of Cancer, shows an increase in body weight during a man's adult life is associated with an increased risk of suffering an aggressive form of prostate cancer and of dying from prostate cancer.
Having a high body mass throughout life was also associated with increased risk of aggressive prostate cancer. "This study and other similar studies have shown that obesity is related to aggressive and fatal cancer," said the study's co-author, Dallas English. "Maintaining a healthy weight during adult life is really the bottom line."
Professor English, director of the centre for molecular, environmental, genetic and analytic epidemiology at the University of Melbourne, said one of his concerns was that the study - of more than 17,000 Australian men aged 40 to 69 - drew participants from a generation in which childhood obesity was not a significant issue.
He said the higher rates of obesity among children now might worsen outcomes. "In Australia, things have changed a lot," he said. "We haven't had the experience of people growing up with childhood obesity."
SOURCE
Daily dose of rosehip extract could help cut heart disease by lowering blood pressure and cholesterol levels
The small changes observed may have no clinical significance. Journal article here
A daily dose of the herbal remedy rose hip could cut the risk of heart disease, new research shows. Obese patients who consumed a drink made with rose hip powder every day for just six weeks saw their blood pressure and cholesterol levels drop significantly.
The tiny berries, which sprout at the end of the rose-blooming season, have been used for centuries as a folk remedy for conditions like arthritis. They are packed with vitamin C and are thought to have powerful anti-inflammatory properties.
One study in 2007 showed patients with sore joints who took a rose hip capsule every day experienced a 40 per cent drop in pain levels and a 25 per cent improvement in mobility.
In the latest research, published in the European Journal of Clinical Nutrition, scientists at Lund University in Sweden recruited 31 obese men and women to see if a daily concoction made with rose hip powder would reduce their risks of developing type two diabetes and heart disease.
Each one spent six weeks drinking the rose hip solution, made with 40 grammes of rose hip powder, followed by six weeks on a drink make from apples and grapes.
At the end of each experiment, researchers measured patients’ body weight, blood pressure, blood fat levels and glucose tolerance - a test to see if they are in the early stages of diabetes.
After six weeks on the rose hip drink, patients saw their blood pressure drop an average of 3.4 per cent, a small but significant decline, and their total cholesterol levels drop by almost five per cent.
Further tests revealed a bigger drop - six per cent - in levels of LDL cholesterol, the ‘bad’ type of blood fat thought to heighten heart disease risks.
Scientists estimated that the drop in cholesterol and blood pressure combined would reduce the risk of heart disease in obese patients by 17 per cent.
And they said if further studies confirmed the cardiovascular benefits of the common garden berry, it could even be used as an alternative therapy for patients who are unable to take the anti-cholesterol drugs statins due to side effects.
In a report on their findings the researchers said: ‘The findings may have important health implications. They may represent an attractive alternative to statin treatment for people that, because of muscle pain and increases in liver and muscle enzymes, do not tolerate statins.
‘The same is true for people at risk of developing diabetes, as statins recently were shown to increase the risk of diabetes.’
SOURCE
Thursday, January 19, 2012
Statins could be linked to increased risk of diabetes
They're treading gingerly here. Once they start talking about statin side-effects, it will open up a real can of worms. The side effects are so numerous that statins will almost certainly eventually be found to reduce lifespans among those who actually take them.
A lot of people who are prescribed them throw them out after a couple of days because of the side effects on memory, muscle tone etc. They may not always tell their doctor that, however.
Journal article here
Cholesterol-lowering drugs known as statins may be linked to an increased risk of diabetes in middle-aged and older women, according to a U.S. study. However, researchers said the benefits of the heart attack-reducing drugs still make them valuable for people at risk.
The study, published in the Annals of Internal Medicine, found that among the thousands of women looked at, those who reported using any kind of statin at the start of the seven-year study were nearly 50 per cent more likely to be diagnosed with diabetes than those not taking statins.
'Statin medication use in postmenopausal women is associated with an increased risk for diabetes mellitus,' wrote Yunsheng Ma of the University of Massachusetts Medical School in Worcester, and his colleagues.
The group used data from the Women's Health Initiative, including more than 150,000 diabetes-free women in their 50s, 60s and 70s.
As part of that larger trial, some of the women were prescribed diet changes or took daily hormone therapy or vitamins, while others weren't told to change their diet or lifestyle.
At the start of the study in the mid-1990s, the women filled out health questionnaires that included whether or not they were taking statins, as well as information on other diabetes risks, such as weight and activity levels. The researchers then followed participants for six to seven years, on average.
In total, just over 10,200 women developed diabetes, with women who reported using any kind of statin - about one in 14 of the participants - 48 per cent more likely to be diagnosed with diabetes than those not taking statins.
That was after considering other known diabetes risks.
Previous studies, mostly in men, have suggested a smaller 10-to-12 per cent increase in diabetes among statin users, said Naveed Sattar, a metabolism and diabetes researcher at the University of Glasgow who did not take part in the study.
Those numbers may be more accurate because they come from trials in which participants were randomly assigned to take a statin or not, which can better account for possible differences in groups of patients, he said, noting that this kind of observational study can't prove cause-and-effect.
The high cholesterol levels that caused the women to take statins may be responsible for the onset of diabetes - rather than the statins themselves. Still, 'broadly speaking, this kind of confirms that statins may well increase diabetes risk,' Sattar said.
The reasons why remain unclear, but the effect of statins on the muscles and liver may lead the body to make slightly more sugar than it normally would, or cause users to exercise a bit less, he added.
While this means that a bit more caution may need to be taken in broad statin use, the benefits still outweigh the potential risk for people with heart disease, he and other experts aid.
Instead, statin users should try to reduce their risk of diabetes in other ways, such as by losing weight and getting more exercise, and should have their blood sugar regularly monitored.
'The conclusion still stands that overall, those people who've got existing heart disease or have had previous strokes, they still would get vast benefit from statins,' Sattar said.
SOURCE
Coffee 'reduces risk of diabetes… but decaff works best
If you are a rat
Drinking coffee can help reduce the risk of diabetes, say scientists. A study found three compounds contained in the beverage can block the toxic build up of a protein, which is known to trigger the long-term condition.
Type 2 diabetes occurs when the body doesn't produce enough insulin for it to function properly but the coffee extracts were also shown to prevent insulin-producing cells from being destroyed. Researchers now believe the coffee extracts - caffeine, caffeic acid, and chlorogenic acid - could help develop more effective treatment.
Lead researcher Kun Huang from Huazhong University of Science and Technology said: 'We found three major coffee compounds can reverse this toxic process and may explain why coffee drinking is associated with a lower risk of type 2 diabetes.'
All of the compounds were shown to have a positive effect during laboratory tests, however caffeine was the least effective of the three. As a result Huang states that decaffeinated coffee could be more beneficial than regular options.
Huang added: 'In decaffeinated coffee, the percentage contents of caffeic acid and chlorogenic acid are even higher [than in regular coffee], whereas the level of caffeine is greatly reduced.
'We expect that decaffeinated coffee has at least equal or even higher beneficial effect compared to the regular caffeinated types.'
The new study, published in the Journal of Agricultural and Food Chemistry, supports previous studies which have found people who drink four or more cups of coffee a day have a 50 per cent lower risk of getting type 2 diabetes.
Despite the findings Joe Vinson from the University of Scranton, highlights that the concentrations of coffee compounds used in the Chinese study are much higher than those found in a typical coffee consumption.
Researchers now plan on carrying out further studies in animals and humans to better understand the link between coffee consumption and reduced risk of diabetes.
Diabetes affects 2.8 million people in the UK and it is thought that a further one million people have the condition but are unaware of it. Type 2 diabetes is often associated with obesity and can often be controlled by following a healthy diet and monitoring blood glucose levels.
SOURCE
They're treading gingerly here. Once they start talking about statin side-effects, it will open up a real can of worms. The side effects are so numerous that statins will almost certainly eventually be found to reduce lifespans among those who actually take them.
A lot of people who are prescribed them throw them out after a couple of days because of the side effects on memory, muscle tone etc. They may not always tell their doctor that, however.
Journal article here
Cholesterol-lowering drugs known as statins may be linked to an increased risk of diabetes in middle-aged and older women, according to a U.S. study. However, researchers said the benefits of the heart attack-reducing drugs still make them valuable for people at risk.
The study, published in the Annals of Internal Medicine, found that among the thousands of women looked at, those who reported using any kind of statin at the start of the seven-year study were nearly 50 per cent more likely to be diagnosed with diabetes than those not taking statins.
'Statin medication use in postmenopausal women is associated with an increased risk for diabetes mellitus,' wrote Yunsheng Ma of the University of Massachusetts Medical School in Worcester, and his colleagues.
The group used data from the Women's Health Initiative, including more than 150,000 diabetes-free women in their 50s, 60s and 70s.
As part of that larger trial, some of the women were prescribed diet changes or took daily hormone therapy or vitamins, while others weren't told to change their diet or lifestyle.
At the start of the study in the mid-1990s, the women filled out health questionnaires that included whether or not they were taking statins, as well as information on other diabetes risks, such as weight and activity levels. The researchers then followed participants for six to seven years, on average.
In total, just over 10,200 women developed diabetes, with women who reported using any kind of statin - about one in 14 of the participants - 48 per cent more likely to be diagnosed with diabetes than those not taking statins.
That was after considering other known diabetes risks.
Previous studies, mostly in men, have suggested a smaller 10-to-12 per cent increase in diabetes among statin users, said Naveed Sattar, a metabolism and diabetes researcher at the University of Glasgow who did not take part in the study.
Those numbers may be more accurate because they come from trials in which participants were randomly assigned to take a statin or not, which can better account for possible differences in groups of patients, he said, noting that this kind of observational study can't prove cause-and-effect.
The high cholesterol levels that caused the women to take statins may be responsible for the onset of diabetes - rather than the statins themselves. Still, 'broadly speaking, this kind of confirms that statins may well increase diabetes risk,' Sattar said.
The reasons why remain unclear, but the effect of statins on the muscles and liver may lead the body to make slightly more sugar than it normally would, or cause users to exercise a bit less, he added.
While this means that a bit more caution may need to be taken in broad statin use, the benefits still outweigh the potential risk for people with heart disease, he and other experts aid.
Instead, statin users should try to reduce their risk of diabetes in other ways, such as by losing weight and getting more exercise, and should have their blood sugar regularly monitored.
'The conclusion still stands that overall, those people who've got existing heart disease or have had previous strokes, they still would get vast benefit from statins,' Sattar said.
SOURCE
Coffee 'reduces risk of diabetes… but decaff works best
If you are a rat
Drinking coffee can help reduce the risk of diabetes, say scientists. A study found three compounds contained in the beverage can block the toxic build up of a protein, which is known to trigger the long-term condition.
Type 2 diabetes occurs when the body doesn't produce enough insulin for it to function properly but the coffee extracts were also shown to prevent insulin-producing cells from being destroyed. Researchers now believe the coffee extracts - caffeine, caffeic acid, and chlorogenic acid - could help develop more effective treatment.
Lead researcher Kun Huang from Huazhong University of Science and Technology said: 'We found three major coffee compounds can reverse this toxic process and may explain why coffee drinking is associated with a lower risk of type 2 diabetes.'
All of the compounds were shown to have a positive effect during laboratory tests, however caffeine was the least effective of the three. As a result Huang states that decaffeinated coffee could be more beneficial than regular options.
Huang added: 'In decaffeinated coffee, the percentage contents of caffeic acid and chlorogenic acid are even higher [than in regular coffee], whereas the level of caffeine is greatly reduced.
'We expect that decaffeinated coffee has at least equal or even higher beneficial effect compared to the regular caffeinated types.'
The new study, published in the Journal of Agricultural and Food Chemistry, supports previous studies which have found people who drink four or more cups of coffee a day have a 50 per cent lower risk of getting type 2 diabetes.
Despite the findings Joe Vinson from the University of Scranton, highlights that the concentrations of coffee compounds used in the Chinese study are much higher than those found in a typical coffee consumption.
Researchers now plan on carrying out further studies in animals and humans to better understand the link between coffee consumption and reduced risk of diabetes.
Diabetes affects 2.8 million people in the UK and it is thought that a further one million people have the condition but are unaware of it. Type 2 diabetes is often associated with obesity and can often be controlled by following a healthy diet and monitoring blood glucose levels.
SOURCE
Wednesday, January 18, 2012
HRT breast cancer alert that led to thousands of women abandoning treatment was 'based on bad research'
I have been pointing this out for years
British research which linked HRT to breast cancer and led to hundreds of thousands of women abandoning the treatment was ‘unreliable and defective’, says a damning review.
It is almost ten years since the study – the largest of its kind – contributed to a worldwide scare about the safety of Hormone Replacement Therapy. It was one of three major pieces of research which undermined the confidence of women and doctors in the therapy.
As a result GPs were advised to prescribe it on a short-term basis only to combat menopausal symptoms such as hot flushes and night sweats. They were also told not to use it as a treatment for the bone thinning disease osteoporosis – which can lead to deadly fractures. An estimated one million women gave up HRT in Britain, halving the number using it.
Scientists at Cancer Research UK’s Epidemiology Unit at Oxford, who carried out the MWS, said HRT doubled the risk of breast cancer and blamed it for an extra 20,000 British cases over the decade.
However, the new review led by Professor Samuel Shapiro, a leading epidemiologist at Cape Town Medical School, South Africa, says the size of the study was irrelevant because the design was flawed and this skewed its findings. Professor Shapiro claims the study failed on a number of criteria accepted in good quality research.
For example, cancers detected within a few months of the study’s start would have already been present when women were enrolled, but these were not excluded and this skewed the findings.
Women in the study were contacted through breast screening – but this in itself would have increased the number already aware of lumps or pre-cancerous changes and led to a bias in higher numbers of cancers being detected.
A key criticism is the ‘biological implausibility’ of HRT promoting new cancers – and of this effect being ‘switched off’ within months of a woman stopping using it.
The researchers also said the name Million Women Study implies an authority beyond criticism or refutation. ‘Size alone does not guarantee that the findings are reliable,’ said the review. ‘HRT may or may not increase the risk of breast cancer, but the MWS does not establish that it does.’
The review, published in the Journal of Family Planning and Reproductive Health Care, is the final in a series looking at research linking HRT to breast cancer, which found flaws in two other major studies.
Review co-author Dr John Stevenson, consultant metabolic physician at Imperial College, London, and Royal Brompton Hospital London, said: ‘So much damage has been done by frightening women off HRT, in terms of reducing their quality of life, preventing bone loss and fractures and improving the risk of cardiovascular disease.
‘HRT is one of the cheapest treatments in medicine and we have yet to count the cost to the NHS because of women not having HRT.’
Professor Dame Valerie Beral, who led the Million Women Study, said the review authors were influenced by work as consultants to HRT manufacturers, and that 20 other studies had come to the same conclusion as MWS. [An "ad hominem" attack is about as weak a rejoinder as you get]
SOURCE
Sweet, sour, salt, savoury, bitter AND fat: Scientists discover that tongue has 'sixth sense' for lipids
If you cannot resist a stodgy cake or chips, it may not be simply down to lack of willpower.
Some of us have a sixth sense of taste – for fat – and those of us who lack it could be more susceptible to piling on the pounds.
For years it was thought that the tongue could detect just four elements of taste – sweet, sour, salt and bitter. Then a fifth ‘savoury’ one was discovered.
Now scientists believe a genetic variant can make some people far more sensitive to fat molecules than others.
Until now, it had been assumed that the desire to eat fatty foods was to do with the sensory system, with some people attracted to its smell and texture.
But the Washington University School of Medicine researchers found that obese people’s cravings for fatty food may be related to their levels of a receptor called CD36.
Those with more of it are better at detecting the presence of fatty food, and seemingly less likely to gorge on it. Twenty-one overweight people were asked to taste solutions from three cups and point to which was different. One contained small amounts of a fatty oil, while the other two were fat-free.
Participants who made the most CD36 were eight times more sensitive to the presence of the fat than those who made around half the amount.
Researcher Professor Nada Abumrad said the finding could help treat obesity by finding a way to increase sensitivity to it.
‘What we will need to determine in the future is whether our ability to detect fat in foods influences our fat intake, which clearly would have an impact on obesity,’ she said.
As people eat more fat, it is possible they need more and more to satisfy their cravings, the researchers told the Journal of Lipid Research.
Previous tests of the CD36 receptor in animals have shown levels of it are not just genetic, but that eating more fat leads to less production of it.
SOURCE
I have been pointing this out for years
British research which linked HRT to breast cancer and led to hundreds of thousands of women abandoning the treatment was ‘unreliable and defective’, says a damning review.
It is almost ten years since the study – the largest of its kind – contributed to a worldwide scare about the safety of Hormone Replacement Therapy. It was one of three major pieces of research which undermined the confidence of women and doctors in the therapy.
As a result GPs were advised to prescribe it on a short-term basis only to combat menopausal symptoms such as hot flushes and night sweats. They were also told not to use it as a treatment for the bone thinning disease osteoporosis – which can lead to deadly fractures. An estimated one million women gave up HRT in Britain, halving the number using it.
Scientists at Cancer Research UK’s Epidemiology Unit at Oxford, who carried out the MWS, said HRT doubled the risk of breast cancer and blamed it for an extra 20,000 British cases over the decade.
However, the new review led by Professor Samuel Shapiro, a leading epidemiologist at Cape Town Medical School, South Africa, says the size of the study was irrelevant because the design was flawed and this skewed its findings. Professor Shapiro claims the study failed on a number of criteria accepted in good quality research.
For example, cancers detected within a few months of the study’s start would have already been present when women were enrolled, but these were not excluded and this skewed the findings.
Women in the study were contacted through breast screening – but this in itself would have increased the number already aware of lumps or pre-cancerous changes and led to a bias in higher numbers of cancers being detected.
A key criticism is the ‘biological implausibility’ of HRT promoting new cancers – and of this effect being ‘switched off’ within months of a woman stopping using it.
The researchers also said the name Million Women Study implies an authority beyond criticism or refutation. ‘Size alone does not guarantee that the findings are reliable,’ said the review. ‘HRT may or may not increase the risk of breast cancer, but the MWS does not establish that it does.’
The review, published in the Journal of Family Planning and Reproductive Health Care, is the final in a series looking at research linking HRT to breast cancer, which found flaws in two other major studies.
Review co-author Dr John Stevenson, consultant metabolic physician at Imperial College, London, and Royal Brompton Hospital London, said: ‘So much damage has been done by frightening women off HRT, in terms of reducing their quality of life, preventing bone loss and fractures and improving the risk of cardiovascular disease.
‘HRT is one of the cheapest treatments in medicine and we have yet to count the cost to the NHS because of women not having HRT.’
Professor Dame Valerie Beral, who led the Million Women Study, said the review authors were influenced by work as consultants to HRT manufacturers, and that 20 other studies had come to the same conclusion as MWS. [An "ad hominem" attack is about as weak a rejoinder as you get]
SOURCE
Sweet, sour, salt, savoury, bitter AND fat: Scientists discover that tongue has 'sixth sense' for lipids
If you cannot resist a stodgy cake or chips, it may not be simply down to lack of willpower.
Some of us have a sixth sense of taste – for fat – and those of us who lack it could be more susceptible to piling on the pounds.
For years it was thought that the tongue could detect just four elements of taste – sweet, sour, salt and bitter. Then a fifth ‘savoury’ one was discovered.
Now scientists believe a genetic variant can make some people far more sensitive to fat molecules than others.
Until now, it had been assumed that the desire to eat fatty foods was to do with the sensory system, with some people attracted to its smell and texture.
But the Washington University School of Medicine researchers found that obese people’s cravings for fatty food may be related to their levels of a receptor called CD36.
Those with more of it are better at detecting the presence of fatty food, and seemingly less likely to gorge on it. Twenty-one overweight people were asked to taste solutions from three cups and point to which was different. One contained small amounts of a fatty oil, while the other two were fat-free.
Participants who made the most CD36 were eight times more sensitive to the presence of the fat than those who made around half the amount.
Researcher Professor Nada Abumrad said the finding could help treat obesity by finding a way to increase sensitivity to it.
‘What we will need to determine in the future is whether our ability to detect fat in foods influences our fat intake, which clearly would have an impact on obesity,’ she said.
As people eat more fat, it is possible they need more and more to satisfy their cravings, the researchers told the Journal of Lipid Research.
Previous tests of the CD36 receptor in animals have shown levels of it are not just genetic, but that eating more fat leads to less production of it.
SOURCE
Tuesday, January 17, 2012
Nutrition therapists condemned as 'quacks' who put patients' health at risk
Nutrition therapists have been condemned as quacks and accused of putting the health of the sick – including those suffering from breast cancer – at risk.
An industry has grown up based on the concept that ‘food doctor’ nutritionists can cure patients’ ills and allergies through diet.
However at least some of the practitioners, who charge up to £80 for a consultation, are providing advice that could harm health, a study by the consumer watchdog Which? found.
The group sent undercover researchers to pose as patients with a range of problems and visit 15 so-called nutritional therapists.
Which? said: ‘They found shocking examples of advice which could have put patients with real health problems at risk.’ All but one of the 15 offered either potentially dangerous or misleading advice. Six of the consultations were rated as ‘dangerous fails’ in terms of misinformation and bad advice. A further eight were rated as ‘fails’, and just one a ‘borderline pass’.
Which? is calling on the Government to regulate the sector which, like much of the cosmetic beauty and anti-ageing industry, has no effective policing regime.
It said: ‘One researcher, posing as a breast cancer sufferer, was told by her therapist to delay radiotherapy treatment recommended by her oncologist, saying they could rid the body of cancer through diet. ‘The therapist advised her to follow a no-sugar diet for three to six months saying, “Cancer feeds off sugar. By cutting out sugar we have a better chance of the cancer going away.”’
This was considered highly irresponsible and incorrect by a panel set up by Which? to assess the advice. It included Professor David Colquhoun, an expert in pharmacology at University College London and a GP, Dr Margaret McCartney.
Another researcher was told if the treatment prescribed for his severe tiredness started to make him feel unwell, it showed that it was working. The therapist advised him not to contact his GP as they ‘wouldn’t understand what was happening’.
Bizarre tests, including iridology, which involves examining patterns in the iris, and hair analysis were also used to ‘diagnose’ conditions.
A researcher who said she had been struggling to conceive was told after having her iris examined she had ‘bowel toxicity’ and a ‘leathery bowel’. Both are meaningless terms, the expert panel said.
Which? found the therapists often used these tests as a part of a sales talk to market unnecessary supplements costing up to £70 a month. Very few of the 15 addressed issues that would have had a positive impact on health, such as reducing alcohol intake.
Prof Colquhoun said: ‘Nutritional therapy is plagued by ‘diagnostic tests’ that are little more than quackery. Iridology and hair analysis simply don’t work.’ Dr McCartney said: ‘If you have symptoms see your GP, not someone who can’t diagnose accurately.’
Which? has decided not to name the therapists involved. However, it has reported its findings to the British Association for Applied Nutrition & Nutritional Therapy (BANT), where a number are registered.
BANT declined to comment.
The British Dietetic Association was keen to make clear its trained dietitians are very different from nutrition therapists such as those visited by Which? BDA said: ‘Anybody can set up shop as a nutrition therapist, with no qualifications. Registered dieticians working in the UK are educated to degree level and must be registered with the Health Professions Council.’
SOURCE
Australia: Women 'overdiagnosed' with breast cancer
There have been similar reports to this from Britain
WOMEN are being treated unnecessarily for breast cancer due to mammograms "overdiagnosing" cancers which would never cause harm, a study has revealed.
In an article published in the Medical Journal of Australia, Monash University breast cancer researchers Robin Bell and Robert Burton called for women invited to use the publicly-funded BreastScreen program to be presented with a more balanced view about the benefits and harms of breast screening.
Their analysis found that improvements in cancer treatments rather than early detection through screening was likely to have caused the 21 to 28 per cent reduction in breast cancer deaths since the program began in 1991.
A 2010 study found that for every 2000 women invited for screening throughout 10 years, one would have her life prolonged but 10 healthy women would be diagnosed as breast cancer patients and treated unnecessarily.
The Cancer Council has backed calls for women to be informed about the risks and benefits of screening, including the uncertainty of overdiagnosis but insist that breast screening has contributed substantially to an overall drop in breast cancer deaths. It said three evaluations of mammography screening for women aged 50-69 years had put the reduction in breast cancer mortality at between 30 and 47 per cent.
Associate Professor Robin Bell said the benefits of the BreastScreen program were overblown. "This comes down to the balance of harm versus benefits," Prof Bell said. "My view is that women need to be given more balanced information about the BreastScreen program when invited to be screened.
"Overdiagnosis amounts to women having a small, slow-growing cancer being diagnosed and treated, where in her lifetime that cancer may not have required treatment."
She said the impact of breast screening was diminishing as the outcome of treatment for breast cancer improved and the balance of benefit to harm of breast screening was becoming less favourable. "This has serious implications for health policymakers," she said.
More than 13,000 women in Australia are diagnosed with breast cancer each year.
SOURCE
Nutrition therapists have been condemned as quacks and accused of putting the health of the sick – including those suffering from breast cancer – at risk.
An industry has grown up based on the concept that ‘food doctor’ nutritionists can cure patients’ ills and allergies through diet.
However at least some of the practitioners, who charge up to £80 for a consultation, are providing advice that could harm health, a study by the consumer watchdog Which? found.
The group sent undercover researchers to pose as patients with a range of problems and visit 15 so-called nutritional therapists.
Which? said: ‘They found shocking examples of advice which could have put patients with real health problems at risk.’ All but one of the 15 offered either potentially dangerous or misleading advice. Six of the consultations were rated as ‘dangerous fails’ in terms of misinformation and bad advice. A further eight were rated as ‘fails’, and just one a ‘borderline pass’.
Which? is calling on the Government to regulate the sector which, like much of the cosmetic beauty and anti-ageing industry, has no effective policing regime.
It said: ‘One researcher, posing as a breast cancer sufferer, was told by her therapist to delay radiotherapy treatment recommended by her oncologist, saying they could rid the body of cancer through diet. ‘The therapist advised her to follow a no-sugar diet for three to six months saying, “Cancer feeds off sugar. By cutting out sugar we have a better chance of the cancer going away.”’
This was considered highly irresponsible and incorrect by a panel set up by Which? to assess the advice. It included Professor David Colquhoun, an expert in pharmacology at University College London and a GP, Dr Margaret McCartney.
Another researcher was told if the treatment prescribed for his severe tiredness started to make him feel unwell, it showed that it was working. The therapist advised him not to contact his GP as they ‘wouldn’t understand what was happening’.
Bizarre tests, including iridology, which involves examining patterns in the iris, and hair analysis were also used to ‘diagnose’ conditions.
A researcher who said she had been struggling to conceive was told after having her iris examined she had ‘bowel toxicity’ and a ‘leathery bowel’. Both are meaningless terms, the expert panel said.
Which? found the therapists often used these tests as a part of a sales talk to market unnecessary supplements costing up to £70 a month. Very few of the 15 addressed issues that would have had a positive impact on health, such as reducing alcohol intake.
Prof Colquhoun said: ‘Nutritional therapy is plagued by ‘diagnostic tests’ that are little more than quackery. Iridology and hair analysis simply don’t work.’ Dr McCartney said: ‘If you have symptoms see your GP, not someone who can’t diagnose accurately.’
Which? has decided not to name the therapists involved. However, it has reported its findings to the British Association for Applied Nutrition & Nutritional Therapy (BANT), where a number are registered.
BANT declined to comment.
The British Dietetic Association was keen to make clear its trained dietitians are very different from nutrition therapists such as those visited by Which? BDA said: ‘Anybody can set up shop as a nutrition therapist, with no qualifications. Registered dieticians working in the UK are educated to degree level and must be registered with the Health Professions Council.’
SOURCE
Australia: Women 'overdiagnosed' with breast cancer
There have been similar reports to this from Britain
WOMEN are being treated unnecessarily for breast cancer due to mammograms "overdiagnosing" cancers which would never cause harm, a study has revealed.
In an article published in the Medical Journal of Australia, Monash University breast cancer researchers Robin Bell and Robert Burton called for women invited to use the publicly-funded BreastScreen program to be presented with a more balanced view about the benefits and harms of breast screening.
Their analysis found that improvements in cancer treatments rather than early detection through screening was likely to have caused the 21 to 28 per cent reduction in breast cancer deaths since the program began in 1991.
A 2010 study found that for every 2000 women invited for screening throughout 10 years, one would have her life prolonged but 10 healthy women would be diagnosed as breast cancer patients and treated unnecessarily.
The Cancer Council has backed calls for women to be informed about the risks and benefits of screening, including the uncertainty of overdiagnosis but insist that breast screening has contributed substantially to an overall drop in breast cancer deaths. It said three evaluations of mammography screening for women aged 50-69 years had put the reduction in breast cancer mortality at between 30 and 47 per cent.
Associate Professor Robin Bell said the benefits of the BreastScreen program were overblown. "This comes down to the balance of harm versus benefits," Prof Bell said. "My view is that women need to be given more balanced information about the BreastScreen program when invited to be screened.
"Overdiagnosis amounts to women having a small, slow-growing cancer being diagnosed and treated, where in her lifetime that cancer may not have required treatment."
She said the impact of breast screening was diminishing as the outcome of treatment for breast cancer improved and the balance of benefit to harm of breast screening was becoming less favourable. "This has serious implications for health policymakers," she said.
More than 13,000 women in Australia are diagnosed with breast cancer each year.
SOURCE
Monday, January 16, 2012
Use a red plate to lose a bit of weight: People who eat off them cut their food intake by 40%
I would find it unpleasant to eat off a red plate and might therefore eat less from it but I would then choose a plate easier on the eye and catch up on my dinner
Eating from a red plate could help dieters lose weight, scientists claim. Serving up meals on red plates or drinking from red cups cuts consumption by about 40 per cent, according to one study carried out by German and Swiss academics.
Researchers say the colour red may encourage diners to avoid snacking because it is commonly associated with the idea of ‘danger, prohibition and stop’.
They claim the discovery means the Government and food industry could use red packaging on unhealthy foods as a deterrent – and could even use more red in pubs to prevent people drinking too much.
In the study, 41 male students were asked to drink tea from cups marked with red or blue labels. They drank 44 per cent less from cups with red labels.
In the second part of the study, 109 people were given ten pretzels each on either a red, blue or white plate. Those with a red plate ate fewer pretzels.
The results were published in the journal Appetite.
Ursula Arens, from the British Dietetic Association, said: ‘Red may be associated with alarm or something primeval.'
SOURCE
Blood test could help to diagnose deadly mad cow disease
A bit concerning that is being released before it is fully validated. A false positive could cause great distress
A new blood test to identify the human form of mad cow disease is being developed by British scientists. Researchers have created the test for the deadly variant Creutzfeldt-Jakob disease (vCJD), which is being offered to British patients for the first time.
Experts said the test represented a “significant step forward” in the fight against the disease as it will enable doctors to find out how many people are infected with vCJD.
Neurologists across the country have been told by the NHS National Prion Clinic, part of the University College London Hospitals Trust, and the Medical Research Council's Prion Unit that the new blood test is now available.
Until now the only way of confirming the diagnosis has been through tonsil biopsies or after the patient has died when brain samples can be taken.
Prof John Collinge, who is leading the MRC team, told Channel Four News that the blood test was "extremely good news". "In principle, it may allow us to find how many people in the population are infected so we can target risk management strategies and ensure the safety of our blood supply," he said.
"It could also enable us to make an earlier diagnosis and as treatments become available it is going to be desperately important to get to patients early before there is extensive damage to the brain.”
Further testing will now occur to ascertain its reliability, which will involve examination of 5,000 anonymous samples supplied by the American Red Cross.
Figures from the Health Protection Agency show there have been 176 cases of vCJD from since it was first detected in humans in 1995.
Variant Creutzfeldt-Jakob Disease is the human equivalent of Bovine Spongiform Encephalopathy (BSE), which affects cattle. Identified in the 1990s, the illness was traced to the consumption of beef products containing contaminated meat.
VCJD progressively causes the brain to become riddled with holes, leading to mental problems, loss of body function, and eventual death. There is no cure. The Department of Health's working estimate is that 1 in 4,000 people - or about 15,000 individuals - are infected.
SOURCE
I would find it unpleasant to eat off a red plate and might therefore eat less from it but I would then choose a plate easier on the eye and catch up on my dinner
Eating from a red plate could help dieters lose weight, scientists claim. Serving up meals on red plates or drinking from red cups cuts consumption by about 40 per cent, according to one study carried out by German and Swiss academics.
Researchers say the colour red may encourage diners to avoid snacking because it is commonly associated with the idea of ‘danger, prohibition and stop’.
They claim the discovery means the Government and food industry could use red packaging on unhealthy foods as a deterrent – and could even use more red in pubs to prevent people drinking too much.
In the study, 41 male students were asked to drink tea from cups marked with red or blue labels. They drank 44 per cent less from cups with red labels.
In the second part of the study, 109 people were given ten pretzels each on either a red, blue or white plate. Those with a red plate ate fewer pretzels.
The results were published in the journal Appetite.
Ursula Arens, from the British Dietetic Association, said: ‘Red may be associated with alarm or something primeval.'
SOURCE
Blood test could help to diagnose deadly mad cow disease
A bit concerning that is being released before it is fully validated. A false positive could cause great distress
A new blood test to identify the human form of mad cow disease is being developed by British scientists. Researchers have created the test for the deadly variant Creutzfeldt-Jakob disease (vCJD), which is being offered to British patients for the first time.
Experts said the test represented a “significant step forward” in the fight against the disease as it will enable doctors to find out how many people are infected with vCJD.
Neurologists across the country have been told by the NHS National Prion Clinic, part of the University College London Hospitals Trust, and the Medical Research Council's Prion Unit that the new blood test is now available.
Until now the only way of confirming the diagnosis has been through tonsil biopsies or after the patient has died when brain samples can be taken.
Prof John Collinge, who is leading the MRC team, told Channel Four News that the blood test was "extremely good news". "In principle, it may allow us to find how many people in the population are infected so we can target risk management strategies and ensure the safety of our blood supply," he said.
"It could also enable us to make an earlier diagnosis and as treatments become available it is going to be desperately important to get to patients early before there is extensive damage to the brain.”
Further testing will now occur to ascertain its reliability, which will involve examination of 5,000 anonymous samples supplied by the American Red Cross.
Figures from the Health Protection Agency show there have been 176 cases of vCJD from since it was first detected in humans in 1995.
Variant Creutzfeldt-Jakob Disease is the human equivalent of Bovine Spongiform Encephalopathy (BSE), which affects cattle. Identified in the 1990s, the illness was traced to the consumption of beef products containing contaminated meat.
VCJD progressively causes the brain to become riddled with holes, leading to mental problems, loss of body function, and eventual death. There is no cure. The Department of Health's working estimate is that 1 in 4,000 people - or about 15,000 individuals - are infected.
SOURCE
Sunday, January 15, 2012
A sausage a day could lead to cancer: Pancreatic cancer warning over processed meat
This appears to be a meta-analysis but there is such a lot of garbage on this subject that all I can do is to repeat the old computer maxim: GIGO (Garbage in; garbage out)
Eating one sausage a day or two rashers of bacon raises the risk of pancreatic cancer by a fifth, according to research. Scientists have found that even relatively small amounts of processed meat increase the chance of developing this deadly illness.
Pancreatic cancer is called ‘the silent killer’ because it often does not produce symptoms in early stages. Even when it does, the symptoms are often vague – such as back pain, loss of appetite and weight loss. By the time the disease is diagnosed it is often too late and, because of this, it has one of the worst survival rates of all cancers and only 3 per cent of patients live beyond five years.
Little is known about its causes other than that smoking, excess alcohol and being overweight all seem to contribute.
Now scientists in Sweden have found that eating just 50g of processed meat a day raises the likelihood by 19 per cent. This is equivalent to a few slices of ham or salami, a hot dog or sausage or two slices of bacon. Eating 100g a day – a small burger – increases the risk by 38 per cent while 150g a day raises it by 57 per cent.
Ordinary red meat such as joints or steaks increases a man’s chance of getting the cancer, but not a woman’s.
But the risk posed by eating meat was substantially lower than for smoking, which was found to increase the likelihood of pancreatic cancer by 74 per cent.
The research, published in the British Journal of Cancer, analysed the results of 11 other studies involving 6,000 patients with pancreatic cancer. There is already widespread evidence that red and processed meat may trigger bowel cancer.
For this reason the Government last year published guidelines advising the public to limit their consumption to 500g of red and processed meat a week.
Professor Susanna Larsson, of the Karolinska Institutet in Stockholm said: ‘Pancreatic cancer has poor survival rates. ‘So it’s important to understand what can increase the risk of this disease.’
Just over 8,000 Britons are diagnosed with pancreatic cancer every year.
SOURCE
Reading any news media will make you live longer?
Boring! Yet another discovery that middle class people have better health
People who keep up-to-date with current affairs are more health-conscious and will live longer, say scientists. A study found those who were most exposed to newspaper, television and the internet had healthier diets than those who were less well informed.
It is now hoped that the findings will help experts to better understand the contribution of mass media in increasing awareness about health.
During the study of more than 1,000 adults, researchers assessed the correlation between exposure to information and eating habits.
They found those most exposed to mass media consumed a healthier diet, with greater quantities of fruit and fresh fish, which reduced the risk of obesity, heart disease and cancer.
Lead researcher Dr Americo Bonanni, from the Catholic University of the Sacred Heart in Rome, Italy, said: 'We focused on eating habits, mainly on Mediterranean diet.
'Results have shown that people most exposed to information delivered by any mass media source, reported higher adherence to the Mediterranean -like eating patterns.
'The latter are considered as the most effective eating model for reducing the risk of chronic and neurodegenerative diseases.'
Past research has often suggested that mass media can have a negative impact on health. For instance television viewing has been linked to physical inactivity and snacking which are major risk factors for obesity and heart disease.
But the latest findings suggest that television programmes, addressing health issues, can also make people more health-conscious.
The participants completed a specific questionnaire on mass media usage, from TV viewing to newspaper and magazine reading and surfing the Internet, which was then analysed alongside medical, lifestyle and dietary data.
More here
This appears to be a meta-analysis but there is such a lot of garbage on this subject that all I can do is to repeat the old computer maxim: GIGO (Garbage in; garbage out)
Eating one sausage a day or two rashers of bacon raises the risk of pancreatic cancer by a fifth, according to research. Scientists have found that even relatively small amounts of processed meat increase the chance of developing this deadly illness.
Pancreatic cancer is called ‘the silent killer’ because it often does not produce symptoms in early stages. Even when it does, the symptoms are often vague – such as back pain, loss of appetite and weight loss. By the time the disease is diagnosed it is often too late and, because of this, it has one of the worst survival rates of all cancers and only 3 per cent of patients live beyond five years.
Little is known about its causes other than that smoking, excess alcohol and being overweight all seem to contribute.
Now scientists in Sweden have found that eating just 50g of processed meat a day raises the likelihood by 19 per cent. This is equivalent to a few slices of ham or salami, a hot dog or sausage or two slices of bacon. Eating 100g a day – a small burger – increases the risk by 38 per cent while 150g a day raises it by 57 per cent.
Ordinary red meat such as joints or steaks increases a man’s chance of getting the cancer, but not a woman’s.
But the risk posed by eating meat was substantially lower than for smoking, which was found to increase the likelihood of pancreatic cancer by 74 per cent.
The research, published in the British Journal of Cancer, analysed the results of 11 other studies involving 6,000 patients with pancreatic cancer. There is already widespread evidence that red and processed meat may trigger bowel cancer.
For this reason the Government last year published guidelines advising the public to limit their consumption to 500g of red and processed meat a week.
Professor Susanna Larsson, of the Karolinska Institutet in Stockholm said: ‘Pancreatic cancer has poor survival rates. ‘So it’s important to understand what can increase the risk of this disease.’
Just over 8,000 Britons are diagnosed with pancreatic cancer every year.
SOURCE
Reading any news media will make you live longer?
Boring! Yet another discovery that middle class people have better health
People who keep up-to-date with current affairs are more health-conscious and will live longer, say scientists. A study found those who were most exposed to newspaper, television and the internet had healthier diets than those who were less well informed.
It is now hoped that the findings will help experts to better understand the contribution of mass media in increasing awareness about health.
During the study of more than 1,000 adults, researchers assessed the correlation between exposure to information and eating habits.
They found those most exposed to mass media consumed a healthier diet, with greater quantities of fruit and fresh fish, which reduced the risk of obesity, heart disease and cancer.
Lead researcher Dr Americo Bonanni, from the Catholic University of the Sacred Heart in Rome, Italy, said: 'We focused on eating habits, mainly on Mediterranean diet.
'Results have shown that people most exposed to information delivered by any mass media source, reported higher adherence to the Mediterranean -like eating patterns.
'The latter are considered as the most effective eating model for reducing the risk of chronic and neurodegenerative diseases.'
Past research has often suggested that mass media can have a negative impact on health. For instance television viewing has been linked to physical inactivity and snacking which are major risk factors for obesity and heart disease.
But the latest findings suggest that television programmes, addressing health issues, can also make people more health-conscious.
The participants completed a specific questionnaire on mass media usage, from TV viewing to newspaper and magazine reading and surfing the Internet, which was then analysed alongside medical, lifestyle and dietary data.
More here
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