Thursday, July 23, 2009



Kids’ lower IQ scores tied to prenatal pollution -- again

This is actually an old claim and as meritless as ever. It just shows that poor and dumber parents live in less desirable and more polluted areas and have dumber kids because IQ is largely inherited genetically. But below we read the usual epidemiological nonsense: Correlation is causation. Logic is obviously not taught in medical schools

Researchers for the first time have linked air-pollution exposure before birth with lower IQ scores in childhood, bolstering evidence that smog may harm the developing brain.

The results are in a study of 249 children of New York City women who wore backpack air monitors for 48 hours during the last few months of pregnancy. They lived in mostly low-income neighborhoods in northern Manhattan and the South Bronx. They had varying levels of exposure to typical kinds of urban air pollution, mostly from car, bus and truck exhaust.

At age 5, before starting school, the children were given IQ tests. Those exposed to the most pollution before birth scored on average four to five points lower than kids with less exposure.

That's a big enough difference that it could affect children's performance in school, said Frederica Perera, the study's lead author and director of the Columbia Center for Children's Environmental Health.

Dr. Michael Msall, a University of Chicago pediatrician not involved in the research, said the study doesn't mean that children living in congested cities "aren't going to learn to read and write and spell."

But it does suggest you don't have to live right next door to a belching factory to face pollution health risks, and that there may be more dangers from typical urban air pollution than previously thought, he said.

While future research is needed to confirm the new results, the findings suggest exposure to air pollution before birth could have the same harmful effects on the developing brain as exposure to lead, said Patrick Breysse, an environmental-health specialist at Johns Hopkins' school of public health.

And along with other environmental harms and disadvantages low-income children are exposed to, it could help explain why they often do worse academically than children from wealthier families, Breysse said. "It's a profound observation," he said. "This paper is going to open a lot of eyes."

The study in the August edition of Pediatrics was released today.

SOURCE






Autism tied to autoimmune diseases in immediate family

It's a very weak link so it is most unlikely to lead anywhere. Autism is far from a unitary phenomenon and a diagnosis of autism can simply mean that communication difficulties are present (along with varied other problems). It is possible that some autoimmune reactions do affect the brain and lead to damage that causes communication difficulties but communication difficulties could arise in various other ways as well.

Danish researchers have found another clue to the mysterious causes of autism, according to a study published online this month in Pediatrics. In a study of children born in Denmark from 1993 to 2004, doctors found that many children with autism or related disorders also had a family history of autoimmune diseases. Autoimmune diseases, such as type 1 diabetes and rheumatoid arthritis, develop when antibodies that normally fight infectious organisms instead attack the body itself.

In the study, doctors examined patterns of disease among children, mothers, fathers and siblings. For the first time, researchers found an increased risk of autism spectrum disorders in children whose mothers have celiac disease, a digestive condition in which people cannot tolerate gluten, a protein found in wheat, rye and barley. Autism spectrum disorders include a range of neurological problems affecting communication and socializing.

The study also confirms the results of many earlier papers, says author Hjördis Atladottir of Denmark's University of Aarhus. For example, doctors found an increased risk of autism in children with a family history of type 1 diabetes and an increased risk of autism spectrum disorders in children whose mothers have rheumatoid arthritis.

Researchers say their study leaves many questions unanswered. But they say it's possible babies are affected by their mother's antibodies while in the womb. Their mother's disease also may create an abnormal environment.

Although the study is designed to find associations among diseases, it is not able to prove that autoimmune disorders cause autism, says the University of Washington's Karen Toth, a clinical psychologist who was not involved in the study. But Toth says it's possible that the same genes are involved in autoimmune diseases and autism. Researchers have known for many years that autism can run in families, Toth says. And scientists have found genes that may be involved in autism.

Children may also have an increased risk if they are exposed in the womb to certain drugs — such as thalidomide, valproic acid or cocaine — or to infectious diseases such as rubella, Toth says.

Recent studies also have found that babies born prematurely have higher risks of autism. Children also are at higher risk if their fathers are older than 40 or if children have conditions such as epilepsy or Fragile X syndrome, which causes mental retardation, according to the Mayo Clinic.

People with autoimmune diseases shouldn't be alarmed, Atladottir says. The vast majority of people with these conditions do not have children with autism, he says. In the study, only 3,325 of the more than 689,196 children studied were diagnosed with autism spectrum disorders.

SOURCE

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