Saturday, November 26, 2011

Well-done steaks 'double prostate cancer risk': Even small amounts of over-cooked meat can be dangerous (?)

Amazing: An agent of the alarmist WCRF actually says something sensible below -- in the first sentence of the penultimate paragraph. She loses it after that, though.

Retrospective self-report is about the weakest data there is but if there is anything in the findings at all, I suspect a social class artifact. Certainly in Australia the people most likely to require their meat to be well-done are the elderly and the working class. The more pretentious you are the rarer you will want your meat.

I remember once going to a very fashionable restaurant in Sydney called Pegrum's and ordering fillet steak done medium. It came out rare and there was much sniffiness when I sent it back to be done medium. I never went there again and they were probably glad of it.

So we are are probably just seeing below the usual poorer health of working class people

An appetite for well-done steaks and burgers could raise the odds of prostate cancer, experts warn. Scrutiny of the eating habits of almost 1,000 men linked over-cooked red meat to the deadliest form of the disease.

Well and very-well done burgers were among the most dangerous meats – doubling the odds of aggressive prostate cancer, even when eaten in small amounts.

Prostate is the most common cancer among British men and the finding suggests that simple changes to diet and cooking routines could help keep it at bay.

The University of California research team recruited 470 men diagnosed with fast-growing and hard-to-treat prostate cancer and a similar number of healthy men and asked them about what they had eaten in the previous year.

They were also asked about their consumption of grilled and barbecued meats, and burgers, liver and some processed meats were linked to higher odds of aggressive prostate cancer.

Further analysis pointed to overcooking at high temperatures as being at the root of the problem. Men who ate grilled or barbecued burgers that were well or very-well done had around twice the odds of aggressive prostate cancer than those who never ate meat or ate it rare or medium-done. The figures for beef, such as steak, were similar.

Previous studies linking red meat to prostate cancer have produced mixed results – but this may be because they did not separate out the most deadly form of the disease and did not focus on overcooking and cooking at high temperatures.

The Department of Health’s scientific advisors said earlier this year that red and processed meat ‘probably’ increases the odds of bowel cancer. They advised eating no more than 70g a day. Over a week, this amounts to three sausages, one small steak, one quarter-pounder and three slices of lamb.

However, a British Nutrition Foundation study claimed that the majority of adults ate ‘healthy amounts’ of red meat and there was an ‘inconclusive’ link to cancer

Dr Rachel Thompson, of the World Cancer Research Fund, said the results could have been skewed by the men mis-remembering what they had eaten, particularly if those with prostate cancer were keen to find something to blame. She added: ‘But looking at cancer overall, there is already a good reason to watch the amount of red and processed meat in your diet.

‘There is very strong evidence that both red and processed meats increase risk of bowel cancer, which is one of the most common types of cancer in the UK, and this is why we recommend that people limit consumption of red meat to 500g per week, cooked weight, and that they avoid eating processed meat.’


Asthmatics given new hope with new air cleaning machine

The average improvement over placebo does not seem to be great but the machine may benefit some more than others

A purification device that cleans the air while asthma sufferers sleep dramatically reduces their symptons during the day, a study has concluded. Researchers reported the drug-free bedside air filter signficantly reduced patients' symptons such as wheezing and tight chests.

The temperature controlled laminar airflow treatment, called Protexo, filters out airborne triggers such as dust particles and mites, pet hairs and powders that cause irritiation and inflamation of the lungs.

Asthma specialists said the low-cost device led to such an improvement in patients' quality of life, that it should be made be available on the NHS. They say the machine achieved results equivalent to those made by expensive drugs and would lead to less time in hospital meaning its £4000 cost would pay for itself. It is also quiet and easy to use.

"This device makes a significant difference to people's lives, with an effect as big as very expensive treatments, and it helps prevent the triggers of the disease," said Prof John Warner, a consultant paediatrician at St Mary's Hospital and professor of paediatrics at Imperial College London, who led the study.

"Our findings support the importance of focusing exposure control interventions on the breathing zone, and highlight the role of nocturnal exposures in precipitating airway inflammation and symptoms in patients with atopic asthma."

The European study of patients, aged seven to 70, found those who used the device recorded 15 per cent better quality of life scores after a year than those given a dummy machine.

Protexo protects the breathing area of people with asthma from allergenic agents with the help of a flow of slightly cooled air around them at night.

Asthma, usually caused by an allergy to airborne dust, pollen or pollution, affects more than 5.1 million Britons and experts warn the number of sufferers is on the rise.

The main medication currently involves taking two types of inhaled drugs, which either help to reduce the frequency of attacks or instantly open up constricted airways, helping breathing.

The researchers, whose findings are published online in the journal Thorax, said Protexo worked by displacing warmer air containing irritants and allergens such as house dust mite and pet hairs with the slightly colder air.

The aim is to stave off the abnormal immune response that triggers an allergic reaction including the airway narrowing typical of an asthma attack by preventing the sleeper breathing in the irritants and allergens. All of the 281 participants in the study from six countries were non-smokers and had poorly controlled allergic (atopic) asthma. A total of 189 patients slept with the Protexo just above their bed for 12 months with 92 others having a placebo.

A validated score was used to assess quality of life before and after the study period along with assessments of symptom control, lung capacity, airway inflammation and biological indicators of a systemic allergic response.

A steeper fall in nitric oxide - an indicator of inflammation - was seen among those using Protexo and this was particularly noticeable among those with more severe asthma.

Those using the device also had significantly smaller increases in another indicator of persistent and more severe inflammation - a chemical known as IgE (immunoglobulin E).

Annabelle Abrahams, 14, from Westcliff-on-Sea, Essex, who has had asthma since she was four, took part in the trial. "I slept badly because I couldn't breathe, doing PE or running around with my friends was difficult and I had asthma attacks if I laughed too much," she said. "My schoolwork suffered because I was tired and off sick a lot."

With the help of the machine, Annabelle now sleeps through the night without coughing. "I've seen a dramatic change and real improvement in my asthma," she said. "I sleep better, have fewer chest infections and enjoy PE and sport."

The impact was greatest among those whose asthma required the most medication yet whose symptoms were the most poorly controlled - a group who "represent a significant area of unmet need," said Prof Warner.

Prof Warner said there were fewer hospital admissions among the group using Protexo. "The reason nocturnal TLA is successful where so many other approaches have failed may be the profound reduction in inhaled aeroallergen exposure, which this treatment achieves," he said.

Despite advances in the treatment of asthma, the condition is still very distressing for a significant proportion of patients.

Previous attempts to filter or purify airflow have not met with a great deal of success.

Prof Warned pointed to other research suggesting night time allergen exposure has the greatest impact on symptom severity, possibly because of changes in circulating hormone levels and immune responsiveness prompted by the body's internal clock, or circadian rhythm.

The machine, which uses the same energy as a lightbulb but is not yet available for private purchase, costs around £2,000 for six months' use.


1 comment:

robrob said...

not sure if this means anything but when I developed asthma i was taking all kinds of stuff, still would get a tightness in my chest at night, so what I did was increase my intake of fruits and veggies and get this saturated fats. real butter, whole dairy (since I am not allergic to it)and cocounut oil. after a few months of eating like this my attacks got less and less, didn't need a rescue inhaler hardly at all. finally I didnt need any meds at all and has been many years since.

by the way it turns out that real saturated fats, not synthetic sat fats, are needed by your air sacs, they need to be 100 percent saturated fats (makes sense if one considers how sat fats are hard to oxidized and damage compared to monos or poly fats while cholesterol is added to teh package and is a strong anti oxidant). dont know if this applies to anyone else but this what helped me.

found it interesting that high carb intake increases glycation of proteins and nerve endings implicated in alzehimers and dementia among other things. when I say high carb I mean high blood serum glucose levels not the food itself, if it enters your blood to fast to often you get this kind of damage when your cells are resistant to glucose. if you glucose sensitive there is less damage.