Monday, July 30, 2012

Night shifts can raise risk of heart attacks and strokes by more than 40%

Ya gotta laugh.  Shift workers had more heart attacks but were not more likely to die young!  So shift work must be GOOD for some other things!

Shift work can dramatically increase the risk of heart attacks and strokes, warn researchers.  A study of two million people found shift workers are almost 25 per cent more likely to suffer.

Night shift workers run the highest risk of 41 per cent, says a study published on the British Medical Journal website

People working shifts also have higher levels of unhealthy behaviours such as eating junk food, sleeping badly and not exercising, which are linked to heart problems.  But researchers said they took this into account - and the excess risks remained.

The latest study is the biggest analysis of shift work and likelihood of vascular problems including heart attacks, strokes and angina.

Shift work has long been known to disrupt the body clock and be linked to high blood pressure, high cholesterol and diabetes, but the overall impact on cardiovascular health has been unclear.

A team of international researchers analysed the results of 34 studies involving 2,011,935 people to investigate whether shift work was associated with major vascular events.

Shift work was defined as evening shifts, irregular or unspecified shifts, mixed schedules, night shifts and rotating shifts, and the studies also contained day workers or the general population for comparison.

Altogether 17,359 had some kind of coronary event, 6,598 had heart attacks and 1,854 had ischaemic strokes caused by lack of blood to the brain.  These events were more common among shift workers than other people.

Shift work was associated with a 23 per cent increased risk of heart attack, 24 per cent rise in coronary events and five per cent extra strokes.

These risks remained consistent even after adjusting for factors such as study quality, socioeconomic status and unhealthy behaviours in shift workers.

Night shifts were linked with the steepest increase in risk of 41 per cent for coronary events.  However, shift work was not associated with increased death rates from any cause.

Daniel Hackam, Clinical Pharmacologist, Stroke Prevention & Atherosclerosis Research Centre (SPARC), London, Ontario, Canada, said the relative risks might appear modest, but millions of people do shift work which means the overall risks are high.

He said screening programmes could help identify and treat risk factors, such as high blood pressure and cholesterol levels.

‘Shift workers should be educated about cardiovascular symptoms in an effort to forestall or avert the earliest clinical manifestations of disease’ he added.

There has been mounting evidence that night shift working might boost cancer risk because of the disruption to the body clock and hormone production.

Previous research found a link between night shifts and increased risk of breast cancer in women.

In 2007 the International Agency for Research on Cancer concluded that shift work was ‘probably carcinogenic’.

More here

Are statins good for asthma?

Admitted below is that the side-effects of statins may make the cure worse than the disease

Asthma sufferers may soon have a new weapon against their condition.  A study suggests those taking the cholesterol-lowering drugs statins alongside inhaled corticosteroids are half as likely to require hospital attention.

Researchers at the University of Mississippi studied 479 patients on statins and inhaled corticosteroids, and 958 just taking corticosteroids.

At least one asthma-related hospitalisation was observed in 3.79 per cent of the first group, compared with 6.47 per cent of the second group.  Those on statins were much less likely to go to A&E – 4.18 per cent compared with 9.08 per cent.

‘This is the most promising study yet,’ says consultant physician Dr Shahid Hamid, at Princess Royal University Hospital in Kent.

‘We know statins have uses beyond the treatment of heart conditions.   'They have anti-inflammatory properties, which means they have other – as yet mostly unexplored – purposes. Asthma is an inflammatory condition so there is clearly a link.’

He says doctors are aware patients admitted to hospital with pnuemonia have a better prognosis if given statins.

‘However, there has been controversy about taking statins for asthma and they may have unpleasant side effects.

‘It is still too soon to start prescribing statins as a matter of course. If you are on statins and have asthma, you must report any change in your condition,’ says Dr Hamid.


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